ʻO ka hoʻomaopopoʻana i ka hana o ka hana i loko o nā scount s9 i loko o nā haʻawina metabolism

I nā hiʻohiʻona Vitro ua lilo i mea nui loa i loko o nā hale kūʻai hou a me nā lāʻau lāʻau lapaʻau,ʻoiai ke nānāʻana i keʻano o ka holomua o nāʻano vivo. ʻO kahi mea hana ākea ākea i kēia mau haʻawinaʻo ia ka hapa nui o S9 i ka hoʻomākaukauʻana, kahi hoʻomākaukau subcollar i loaʻa mai i nā homorontes a me nā cytosolic. Hāʻawi kēia mau hana i ka loiloi kūpono o Xenobionictic metabolism, equigili, a me ka metabolic ho'ālaʻana i nā mea hōʻike.

'ŌleloS9 FractionʻO ka maʻamau maʻamau i loaʻa mai i nā'ōpala o nā'āpana o nā rodents-rats a me nā hamsters ka mea maʻamau-precurte maʻamau ʻO ka hoʻohālikelikeʻiaʻo S9 i hoʻohālikelikeʻiaʻo S9 kāwili i ka paila e like me nā mea e like me cytochrome p450 i nā glucugation e like me nā glucugansfessferes. ʻO kēia Dual - He mea nui ka heleʻana o Rightme i ka wā e nānā ana i nā ala paʻakikī metabolic ma kahi kūlana hana.

Ka hana oInucd rat liter s9

Inucd rat liter s9ʻo ia ka mea i hoʻohana pinepineʻia,ʻoi aku ka nui o nā hoʻokolohua genotkicatinity e like me nā aʻa e like me nā mea e hoʻopiʻi ai a iʻole ka hōʻike micronucleus. Ua hoʻomākaukau pinepineʻia kēia mau hana ma hope o ka lā. ABOCLOR 1254, i loko, ua nui loa, i hoʻohana nuiʻia e hana i ka acedror - He mea nui kēia no ka simulating i ka hana enzyme i loaʻa i loko o vivo, e hoʻolako i kaʻike koʻikoʻi i loko o kahiʻano o keʻano.

Nā noi no ArClor - Hoʻokomoʻia S9 i:

• ʻO ka ho'ākākaʻana i ka hana mammania mammabolina ma nā mea waiwai mika

• Ke noiʻi neiʻo Hanna I BINATESHANCHES

• Ke wānana nei i ka metabolism o ke kanaka ma ke aʻoʻana i nā analginactural Analogs
  
  
  
  

I ka wa e hoʻohana aiIndid shster live s9

ʻOiaiʻo nā rats ka maʻamau ma nā hana he nui,Indid shster live s9hāʻawi i kahiʻano hōʻike likeʻole e like me ka hana likeʻole. ʻO kekahi mau hui pū kekahi metabilima e like me nāʻano kiko'ī ʻO kēia mea i haehae i keʻano o ka noiʻiʻana a me nā kōkua e hōʻemi i nā negatives a iʻole e pili ana i nā mea i hanaʻia e nāʻano bias.

No ka noʻonoʻoʻana i ka hoʻohana s9

Ke kohoʻana i kahi'ōnaehana i kūʻaiʻia ma ka'ōnaehana S9 ka mea e noiʻi ai nā mea noiʻi.

• Keʻano o ka hoʻohui (pro - lāʻau lapaʻau lāʻau lapaʻau vs. Direction -

• ʻO keʻano o nā enzymes e koiʻia (Oxidation vs. Conjugation Dinant)

• ʻO nā mea hoʻoponopono Regulatory

• ʻO ka hana nui a me nā hana e hoʻonui ai i ka hana o ka hapa s9
  
  
  

IPhise: Kākoʻo hilinaʻi no S9 - Nā noiʻi metabolilika

At Iphoe, ua hoʻomaopopo mākou i ka paʻakikī o keʻano o ka wā e hoʻomaka ai. Hāʻawi mākou i nā mea i hoʻopaʻaʻia i nā hua'ōlelo s9, i hoʻopaʻaʻia i ka ratud s9, i hoʻopaʻaʻia i ka hamster liv, a hui pūʻia ma lalo o nā protocols maikaʻi loa. Ua ho'āʻoʻia kēlā me kēia batch no ka hana enzymatic a me ka nui - i - nui nui, e hōʻoia i nā hualoaʻa a me nā hopena hou aʻe ma kahi o nā haʻawina vitro.

Me kaʻikeʻana i ke kākoʻoʻana i ka honua honua honua, kaiāulu, a me nā goctinutions, nā mea e hilinaʻi nuiʻia ma ka hāʻawiʻana i nā mea noiʻi subcerl Hanaʻia kā mākou mau huahana S9 mai nā holoholona i hanaʻia e ka poʻe hana i hoʻopaʻaʻia a paʻaʻia e like me nā loiloi iʻikeʻia e pili ana i nā koina o nā koina o keʻano o nā koina.