Kainga ADME IPHASE Tangata CYP2D6 + reductase

IPHASE Tangata CYP2D6 + reductase

Whakaahuatanga Poto:

Ko nga whākōkī CYP450 recombinant ka riro mai i te hangarau ira o nga ira CYP450 ka whakaatuhia ki roto i te E. coli, i nga pūtau pepeke ranei. Ko te takitahi CYP450 isoenzyme ka whakaatuhia, ka purea, ka whakamahia ki te ako i te paopaotanga tarukino, te polymorphism metabolism tarukino me te taunekeneke i te tarukino. Ka taea te whakamaarama i nga momo rerekee o te paopaotanga tarukino ma te whakatairite i nga tohu metabolites o nga kaitono tarukino ma te ate CYP450 enzymes.

WHAKAPAKI NEI Tāpirihia ki te kaata hokohoko

Taipitopito Hua

Tohu Hua

Whakaahuatanga hua

N/A

Kāwai:
Reductase
Te nama take:
0161A1.07
Rahi Waeine:
0.5mL,0.5nmoL
Kopa:
N/A
Momo:
Tangata
Sex:
N/A
Nga tikanga rokiroki me te kawe:
Rokiroki i te -70°C. Te huka maroke kua tukuna.
Pūnaha Whakamātautau:
Whakakotahitanga CYP450 whākōkī
Te whānuitanga o te tono:
In Vitro Drug Metabolism Studies

Tōmua: IPHASE Tangata CYP2E1 + reductase

Panuku: IPHASE Tangata CYP2C19 + reductase

IPHASE Tangata CYP2D6 + reductase

Whakaahuatanga Poto:

Taipitopito Hua

Tohu Hua

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