Magazi opotoza a anthu mononuclear cell (PBMC)
PBMC imatha kulemba - Vivo Creation kuti ipereke zothandiza mu - Vitro chitsanzo cha kukula kwa mankhwala. Kuwerenga zotsatira za mankhwala osokoneza bongo komanso njira zowunikira za ma pbmc zimatha kuthandiza kupeza zomwe zatsala, ndipo zomwe zipezeka zimatha kupereka malingaliro ndi mayendedwe osawerengeka.
Malangizo akuluakulu a PBMC mu Imnotherauutic Kukula kwa mankhwalawa kumaphatikizapo:
1.Antribd - Cell yodalirika - Cytotoxicity (ADCC): PBMM): PBMM) Maselo a NK, Macrophages, ndi zina. Maselo amenewa amatha kupha maselo osindikizidwa ndi ma antibodies pomanga nawo.
2.Mixed lympocyte ady (Mlr): Chikhalidwe cha CO - Chikhalidwe cha CC cha DC Slassion ndi ma T - Ma cell a DC amafotokozera kuchuluka kwa PD - L1 pamtunda wawo, womwe ungamangire ndi zoletsa pd - 1 Pamalo a T. Ngati mankhwalawa atha kutseka panjira ya awiriwo pakati pa awiriwa, ndiye kuti amatha kulimbikitsa kuchuluka kwa ma cell a T ndikutsimikizira ntchito ya mankhwalawa.
3.T ma cell oyambitsa maselo: TV TAMPES Cell ndi imodzi mwazinthu zomwe zimagwiritsidwa ntchito powunikira zotsatira za immungurap mankhwala. Mu Celly Kuyambitsa maselo, mu - mu - maselo odziwika bwino a T nthawi zambiri amagwiritsidwa ntchito komanso zokopa zoyenera, monga ma antigans kapena ma antibodies, amaperekedwa kuti apangitse kutsegula kwa ma cell a T.
4.T Cell Plallarration Agal: TLOR CLARDE CELAY ikhoza kugwiritsidwa ntchito poyang'ana Imnutherapy ogwiritsa ntchito ndi kuyerekezera bwino mankhwalawa poyerekeza kuchuluka kwa kuchuluka kwa mankhwala osokoneza bongo.
Masamba a anthu omwe amapangidwa ndi Iphase amapatula magazi otumphukira ndi mitundu yosiyanasiyana ya centriftion. Awa ndi ma cell osakwatiwa amodzi omwe amapangidwa ndi ma cell a lympocytes (ma cells, ma b, ndi maselo a NK) ndi ma cell.
▞ chidziwitso chazogulitsa:
|
Dzina |
Chinthu Ayi. |
Chifanizo |
Mawonekedwe a cell |
Kusungira / Kutumiza |
|
Ma cell a anthu opotoka a anthu |
082a01.11 |
Maselo 5 miliyoni / ml |
Chatsopano |
2 - Kusungirako 8 ˚˚, kutumizidwa kwa ayezi |
▞ Ntchito Yogulitsa:
Mu - vits metabolism kuphunzira mankhwala.
