Aiga ADME IPHASE Vaega II Pusa mautu Metabolic, Iole(Sprague-Dawley)

IPHASE Phase II Metabolic Stability Kit, Rat(Sprague-Dawley)

IPHASE Vaega II Pusa mautu Metabolic, Iole(Sprague-Dawley)

Fa'amatalaga Puupuu:

Vaega II metabolism, lea e taʻua foi o le fusifusia tali, e faasino i le tali lea o le vaega I metabolites poʻo vailaʻau faʻataʻitaʻiga e tuʻufaʻatasia ma molelaʻau laiti e ala i le vaega II enzymes, e oʻo atu ai i le faʻaitiitia o le oona, gaioiga, poʻo le polarity o prodrugs. I le vaega II metabolism, o le tali sili ona taatele o le glucuronidation, lea e fusifusia ai le uridine diphosphate glucuronic acid (UDPGA) i le prodrug e ala i le catalyzation e le glucuronyl transferase i microsomes. O le glucuronide e fa'atupuina e fa'atuputeleina ai le vai-solubility o metabolites e fa'aleleia ai le alu. O le vaega II metabolic system e mafai ona toe faʻaleleia e ala i le tuʻufaʻatasia o le ate microsomes ma le UGT ma faʻaaoga e suʻesuʻe ai le tulaga II metabolic mautu o sui tauva fualaau faasaina in vitro.

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Microsome｜Substrate｜ UGT Incubation System｜ 0.1M PBS (pH7.4)

Vaega:
In vitro metabolism pusa
Numera Numera:
0112D1.01
Tele Vaega:
0.2mL*50 su'ega
Tisu:
ate
Ituaiga:
Iole
Ituaiga:
Male
Tulaga teuina ma felauaiga:
Teu i le -70°C. Aisa mago tiliva.
Ituaiga Su'ega:
Pusa Fa'amautuga Metabolic Vaega II (UGTs)
Faiga Su'ega:
Microsome
Avanoa o le talosaga:
Su'esu'ega in vitro o le mautu o le Metabolic

Muamua: IPHASE Vaega II Pusa mautu Metabolic, Iole(Sprague-Dawley)

Sosoo ai: IPHASE Vaega II Metabolic Stability Kit, Beagle

IPHASE Vaega II Pusa mautu Metabolic, Iole(Sprague-Dawley)

Fa'amatalaga Puupuu:

Fa'amatalaga Oloa

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