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Soosaarayaasha kaadida daanyeer, alaab-qeybiyeyaal, warshad

Shirkaddu waxay u doodaa ujeedada ganacsiga ee tayada-ujeeda, daacad u ah xarafka, adeegga marka hore, waxayna leedahay awood farsamo oo xoog leh, heer sare- heer maarayn ah iyo sidoo kale awood wax soo saar oo xooggan. Iyada oo la raacayo ujeedada ganacsiga ee loogu adeegayo macaamiisha si daacad ah, waxaan bixinaa alaabooyinka ugu horreeya iyo adeegga hufan ee daanyeerka - kaadida,xirmada bile jiirka, xirmada balasmaha daanyeer, Xidhmada tusbaxa CD3/CD28, xirmada jiirka CD3+T. Waxaan taageernaa fikradda adeegga "xamaasadda leh, daacadda ah, taxaddarka leh iyo maskaxda marka hore". Shirkaddu waxay leedahay koox farsamo oo xirfad leh, kuwaas oo horumarin kara xalal shakhsi ahaaneed sida waafaqsan baahida macaamiisha. Waxaan u hoggaansanahay isticmaalaha xarun ahaan, u hoggaansanaanta "fudud, fududahay in la isticmaalo, la isku halleyn karo" fikradda naqshadaynta alaabta. Iyadoo fiiro gaar ah loo leeyahay waayo-aragnimada isticmaalaha, waxaan si buuxda u tixgelinaynaa isticmaalka dhabta ah ee muuqaalka isticmaalaha. Waxaan bilownay taxane ah qaab gaar ah oo badeecado aad u fiican. Had iyo jeer waxaan u hoggaansanahay astaanta asalka ah. Hadda waxaan haynaa dhowr shati-hal-abuur oo gudaha iyo dibadda ah. Waxaan sidoo kale ku guuleysanay abaalmarino badan oo naqshadeynta. Shirkaddu waxay gelaysaa marxalad horumarineed oo joogto ah oo degdeg ah, iyadoo siinaysa shaqaalaha madal horumarineed oo wanaagsan. Waxaan si daacad ah ugu yeernay xirfado ka kala socda qeybaha kala duwan ee nolosha inay nagu soo biiraan. Aan si wadajir ah u abuurno sabab weyn oo aan gaadhno mustaqbal wanaagsanxirmo PBMC feline, balasmaha daanyeer, kelyaha S9 jajab, xirmada eyga beagle ee CSF.

Alaabooyinka La Xiriira

IPHASE Human Peripheral Blood CD8+T Cells,frozen — IPHASE Unugyada Dhiigga Xudunta ah ee CD8+T, barafoobay
Sii akhri

IPHASE Plateable Rabbit(Japanese White) Hepatocytes — IPHASE Plateable Bakaylaha (Japanese Cadaan) Hepatocytes

IPHASE Monkey Lung Tissue — IPHASE Monkey Sanbabada

IPHASE Monkey(Cynomolgus) PBMC,fresh — IPHASE Daanyeer (Cynomolgus) PBMC, cusub

IPHASE Mouse(ICRN/ACD-1) Whole Blood,Mixed Gender,EDTA-K2,Fresh — Jiirka IPHASE(ICRN/ACD-1) Dhiig Dhan, Jinsi Isku Dhan, EDTA-K2, Cusub

IPHASE Plateable Monkey(Rhesus) Hepatocytes — IPHASE Daanyeer La Sameeyo (Rhesus) Hepatocytes

IPHASE Monkey (Cynomolgus) Liver Microsomes — IPHASE Daanyeer (Cynomolgus) Beerka Microsomes

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Novel in vitro hepatocyte-hab dheef-shiid kiimikaad ayaa sahlaysa gaabis -

Maaddaama dawada dheef-shiid kiimikaadka enzyme-ka ay si tartiib tartiib ah u yaraato iyadoo la dheereynayo waqtiga soo-jiidashada gudaha vitro, moodooyinka dheef-shiid kiimikaadka ee dhaqameedku waxay leeyihiin xaddidaad sida waqti gaaban oo tallaal ah.
Waa maxay habka firfircoonida unugga T?

Unugyada HordhacT waa qayb muhiim ah oo ka mid ah habka difaaca jirka, iyaga oo door muhiim ah ka ciyaara aqoonsiga iyo la dagaallanka cudurada. Habka hawl-gelinta unugga T waa kakan, badan- makaanis tallaabo ah
Waa maxay go'doominta unugyada T?

Horudhac ku saabsan go'doominta unuggu waa geedi socod muhiim ah labadaba cilmi baarista sayniska iyo codsiyada caafimaadka, taas oo awood u siinaysa soo saarista unugyo gaar ah oo T unug isku dhafan oo loogu talagalay daraasado kala duwan. Habkani waa lama huraan xagga hoose-yada
Xalka in vitro mRNA daraasadaha dheef-shiid kiimikaadka

Horudhaca dawooyinka mRNA Messenger RNA (mRNA) waa taxane nucleotide ah oo soo koobaya borotiinka, iyo cytoplasm dhexdeeda waxa uu awood u leeyahay inuu isticmaalo organelles si uu u muujiyo borotiinka qarsoon. Daawooyinka mRNA waa kiimiko
Ka qayb galka shirka Jaalliyadaha Ameerikaanka ee Shiinaha ee Mass Spectrometry (CASMS).

Waxaan ku faraxsannahay ka qaybgalka shirweynaha Bulshada Ameerikaanka ee Mass Spectrometry (CASMS) ee Noofambar 1-deeda! Waxay ahayd maalin dhiirigelin leh oo ku xidhnayd xirfadlayaasha warshadaha iyo helitaanka fikrado horumarradii ugu dambeeyay ee spectrometry mass.
IPHASE waxay si xooggan uga soo muuqatay Madasha Hal-abuurka Reer Galbeedka, iyadoo muujisay awooddeeda aan caadiga ahayn!

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Kyler6:41 AM

Sida shirkad aad u fiican, waxay leeyihiin koox xirfad leh, oo leh khibrad qani ah, iyo nidaam xisaabeed adag. aan isticmaalno mid aad u fudud!
Caiden6:06 subaxnimo

Alaabooyinkoodu maaha oo kaliya inay leeyihiin tayo sare leh, laakiin sidoo kale waxay isticmaalaan hababka deegaanka saaxiibtinimo, taas oo aad u badan oo la socota falsafada horumarintayada.
Ishaan1:26 AM

Waxaan nasiib u yeelanay inaan la shaqeyno shirkaddan alaabteedu ay yihiin kuwo tayo deggan, gaarsiin degdeg ah iyo qiimo macquul ah.
Roland3:50 galabnimo

Waxaan la shaqaynaynay muddo 3 sano ah. Waxaan aaminsanahay iyo abuurista labada dhinac, saaxiibtinimada wada noolaanshaha. Waa guul-horumar guuleed. Waxaan rajeyneynaa in shirkaddani ay noqon doonto mid ka sii wanaagsan oo ka sii wanaagsan mustaqbalka!
Santino7:15 galabnimo

Waxaan dareensanahay in la-shaqeynta shirkaddaadu ay tahay fursad aad u wanaagsan oo lagu barto. Waxaan rajaynaynaa inaan si farxad leh u wada shaqayno oo aan mustaqbal wanaagsan wada abuurno.
Axl5:15 subaxnimo

Alaabta si degdeg ah ayaa loo raray. Tayada ayaa ah mid aad u wanaagsan. Shaqaalaha xirfada leh ee shirkadu waxay na siiyeen caawimo badan, mahadsanid!