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The in vivo alkaline comet assay has been increasingly used in the genotoxicity evaluation of compounds. ICH S2(R1) has included the liver comet assay as the 2nd in vivo test for tissues/endpoints; an
Introduction to mRNA drugs Messenger RNA (mRNA) is a sequence of nucleotides that encodes a protein, and in the cytoplasm is able to use organelles to express the encoded protein. mRNA drugs are chemi
Micronuclei are whole chromatids or acentric fragments or ring chromosomes which remain in the cytoplasm when chromosomes regularly enter daughter cells to form nuclei after mitosis.
How to Prepare Slides for Comet Assay
The comet assay, also known as single-cell gel electrophoresis, is a sensitive and versatile technique for quantifying DNA damage in individual cells. Preparing h
We were excited to take part in this year's Chinese Biopharmaceutical Association – Greater Philadelphia (CBA-GP) Annual Conference, an event that brought together an impressive community of sch
Recently, IPHASE, in conjunction with the Perelman School of Medicine at the University of Pennsylvania, co-authored an article in the journal Antibody Therapeutics (IF=4.56) titled "Development of a
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