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Introduction to mRNA drugs Messenger RNA (mRNA) is a sequence of nucleotides that encodes a protein, and in the cytoplasm is able to use organelles to express the encoded protein. mRNA drugs are chemi
The in vivo alkaline comet assay has been increasingly used in the genotoxicity evaluation of compounds. ICH S2(R1) has included the liver comet assay as the 2nd in vivo test for tissues/endpoints; an
How to Prepare Slides for Comet Assay
The comet assay, also known as single-cell gel electrophoresis, is a sensitive and versatile technique for quantifying DNA damage in individual cells. Preparing h
Introduction
T cells are an essential component of the immune system, playing a critical role in identifying and combating pathogens. The process of T cell activation is a complex, multi-step mechanis
Introduction to Liver Microsomes
Microsomes are small vesicular fragments derived from the endoplasmic reticulum and are found within liver cells (hepatocytes). They play a crucial role in various bio
Recently, IPHASE, in conjunction with the Perelman School of Medicine at the University of Pennsylvania, co-authored an article in the journal Antibody Therapeutics (IF=4.56) titled "Development of a
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