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Antibody-Drug Conjugate (ADC) is a relatively new type of biotechnology drug which couples small molecule therapeutic compounds to targeting antibodies/antibody fragment by linkers.
The in vivo alkaline comet assay has been increasingly used in the genotoxicity evaluation of compounds. ICH S2(R1) has included the liver comet assay as the 2nd in vivo test for tissues/endpoints; an
Introduction to Liver Microsomes
Microsomes are small vesicular fragments derived from the endoplasmic reticulum and are found within liver cells (hepatocytes). They play a crucial role in various bio
Recently, IPHASE, in conjunction with the Perelman School of Medicine at the University of Pennsylvania, co-authored an article in the journal Antibody Therapeutics (IF=4.56) titled "Development of a
Since the drug metabolizing enzyme activities gradually decrease with the prolongation of in vitro incubation time, traditional in vitro metabolism models have limitations such as short incubation tim
We were excited to take part in this year's Chinese Biopharmaceutical Association – Greater Philadelphia (CBA-GP) Annual Conference, an event that brought together an impressive community of sch
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