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The in vivo alkaline comet assay has been increasingly used in the genotoxicity evaluation of compounds. ICH S2(R1) has included the liver comet assay as the 2nd in vivo test for tissues/endpoints; an
Introduction to mRNA drugs Messenger RNA (mRNA) is a sequence of nucleotides that encodes a protein, and in the cytoplasm is able to use organelles to express the encoded protein. mRNA drugs are chemi
PDC in vitro ADME research model PDC takes into account the characteristics of both large and small molecules. Therefore, in vitro ADME research on it needs to take into account homing peptides, linke
Introduction to Tritosomes
● Definition and Significance
Tritosomes are specialized subcellular structures involved in various cellular processes, particularly in the regulation of metabolic pathways
How to Prepare Slides for Comet Assay
The comet assay, also known as single-cell gel electrophoresis, is a sensitive and versatile technique for quantifying DNA damage in individual cells. Preparing h
Introduction to B Cells and Their Importance
In the intricate web of the human immune system, B cells play a pivotal role. As a type of white blood cell, B cells are integral to the adaptive immune re
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