News
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What Are Rat Tritosomes and Why Do They Matter in Research?
In the field of biomedical and molecular research, understanding cellular compartments is essential for dissecting the complexities of cellular function and disease mechanisms. Among these compartmentRead more -
Sulfotransferase(SULT) for DDI Research, Metabolic Stability, and Enzyme Inhibition
Key words: drug-drug interaction (DDI), sulfotransferase (SULT), enzyme inhibition, SULT metabolic, metabolic stability, human SULT1A1 enzyme, human SULT1A3 enzyme, human SULT1B1 enzyme, human SULT1C2Read more -
Carboxylesterases (CES) in Drug Metabolism: Reaction Phenotyping and DDI
Keywords: Drug-Drug Interaction(DDI), Carboxylesterase 1, Carboxylesterase 2, CES1, CES2, Liver Carboxylesterase, Intestinal Carboxylesterase, CES Enzyme Inhibition, Drug Metabolic Stability, ReactionRead more -
Application of Cytochrome p450 (CYP450) and UDP-glucuronosyltransferase (UGT) Enzymes in Drug-drug Interaction Studies Regarding Metabolic Phenotype and Enzyme Inhibition
Key words: drug-drug interaction (DDI), cytochrome p450 (CYP450 enzyme), udp-glucuronosyltransferase (UGT), Enzyme inhibition, CYP450 enzyme metabolic phenotyping study, CYP1A2, CYP2B6, CYP2C8, CYP2C9Read more -
Human & Animal Bile of Blank Biological Matrix for Bioanalytical Method Development and Bioanalytical Method Validation
1 IPHASE Products Product Name Specification IPHASE Human Bile 2mL IPHASE Monkey Cynomolgus/Macaca Fascicularis Bile,Single Donor,Male 2mL IPHASE Monkey Cynomolgus/Macaca FascicuRead more -
Cross Species Cerebrospinal Fluid Analysis (CSF Analysis) and Artificial Matrix Development: Solving Key Technical Bottlenecks in CNS Drug Bioanalysis
1 IPHASE Products Product Specification IPHASE Human Cerebrospinal Fluid 1mL IPHASE Monkey Cynomolgus/Macaca Fascicularis Cerebrospinal Fluid,Male 1mL IPHASE Monkey(Rhesus) CerebRead more -
5α-Reductase Activity Study: SRD5A1 & SRD5A2 for Sebum Control in Cosmetic Science
Keywords: Type 1 5α-Reductase, Type 2 5α-Reductase, 5αR1, 5αR2, SRD5A1, SRD5A2, NADPH, 5α-Reductase Activity, 5α-Reductase Inhibition, Dihydrotestosterone(DHT). IPHRead more -
Induced Rat Liver S9 Fraction: A Metabolic Activation System for In Vitro Genotoxicity and Mutation Tests
Keywords: OECD 471, OECD 473, OECD 476, OECD 487, Mutation Test, Genotoxicity, Genetic Toxicity, Induced Rat Liver S9, Ames Test, Mini Ames Test, Chromosomal Aberration, Micronucleus, HPRT/HGPRT AssayRead more -
Understanding the Role of Induced S9 Fractions in Drug Metabolism Studies
In vitro models have become indispensable in modern toxicology and pharmacokinetics, particularly when assessing how a compound behaves metabolically before progressing to in vivo stages. One widely aRead more -
Plasma Protein Binding Dynamics: Equilibrium dialysis and Ultrafiltration Methods and Application in DDIs
Keywords: Equilibrium Dialysis, Ultrafiltration, Plasma Protein Binding(PPB), Binding rate of plasma protein(BRPP), Equilibrium Dialysis Device, Equilibrium Dialysis Membrane, Rapid Equilibrium DialysRead more -
IPHASE Bioscience Showcases Innovative ADME-Tox Solutions at Lunch & Learn Event in Doylestown
IPHASE Biosciences Showcases Innovative ADME-ToxSolutions at Lunch & Learn Event in Doylestown On April 9th, IPHASE Biosciences held a successful Lunch and Learn event at Pennsylvania Biotechnology CRead more -
Transporters and Their Roles in Pharmacology
Transporters and Their Roles Transporters are a broad class of transmembrane proteins that span the cell membrane of many tissues and play an essential role in controlling the passage of endogenous (nRead more