Imwe - STM Solution Solution yeVitro Adme Zvidzidzo zveAocs Zvinodhaka

Revolutionary Therapeutics: Anti Boy - Oligonucleotide Conjugates (AOCS) - Iyo Ramangwana Rekunyatsoita Mushonga

Pasi rinokurumidza kusimudzira nyika yebhurugwa,Anti Body - Oligonucleotide Conjugates (AOCS)vari kubuda sekirasi yepamhepo yemishonga yemishonga, vachisanganisa simba rakananga rekutarisa kweantibodies neGene - Kuwanira kugona kweOligonucleides. Aya marapirwo ekugadzira akagadzirirwa kuendesa Oligonucleideides-pfupi tambo dzeDNA Uyu Dual - Maitiro Ekuita Anoshandisa mikana mitsva yekugadzirisa mamiriro akaoma senge cancer, genetic kusagadzikana, uye kuzvirwere zvemunehurongwa.

Nei AOCs Acers Caners

AOCS yakaumbwa nezvinhu zvitatu zvakakosha: Antibody, osponulleotefude, uye linker. Uku kusanganisa kwakasarudzika kunoda kunyatsofungisisa panguva yekukura, kunyanya muPamsacokinetic zvidzidzo. Kusiyana nemishonga madiki madhiragi madhiragi, oligonucleides ane hunhu hwakasarudzika-hwakadzika huremu, hukuru hwakasimba, hwekupomera kwakashata, kunova nemhosva yakanyanya-inovaita vakasiyana zvakanyanya. Mukutanga kwekutanga zvinodhaka, zvakakosha kuti uitePlasma / Serum Stability ZvidzidzoKuve nechokwadi cheiyo oligonucleide chikamu chinoramba chakasimba, sezvo ivo vanokanganiswa nekushatiswa nemidziyo. Kugadzikana uye kusunungurwa kweOligonuCledide mumasero akanangwa zvakakosha pakubudirira kweAOCS.

Uyezve, nzira yekubatanidza iyo oligonucleotedide kune antidy inokanganisa zvakananga kuti mushonga unoburitswa mukati mechitokisi, kunyanya muRysosomes. Chinhu ichi chinonetsa zvinoreva kuti AOCS inoda nzira dzakasarudzika dzeBioanalytical dzePharmacokinetic zvidzidzo, zvichiita kuti gadziriswe gadziriro yavo uye kuongororwa kwakakosha kune kwavo kugona.


Na Olksandr Koniev - Basa Rako, CC na - SA 4.0

Ifase: mumwe wako muAOC hunyanzvi

KuPahase, isu tiri kutsigira iyo inotevera wave yeACOC DUBP BEST NEMUDZIMA - EGRATEmu vitro bio - reagents. Nezvikamu zvakazara zve bio - reagents, isu tinobatsira vatsvagdenga vanowana kubudirira muAC ACOC zvinodhaka nekuvandudza. Yedu yakakura portfolio yeAdme Research Refagents

Nemakore ehunyanzvi uye ruzivo, Iphase inopa azadzisa suite mu vitro research reagentsKune zvinodhaka uye kupfuura. Kunyangwe iwe urikukudziridza aocs, madiki madiki, kana chero imwe kirasi yezvinodhaka, Iphase yakazvipira kupa mhinduro dzaunodakutyaira kutsvagisa kwako kumberiuye uyai nechizvarwa chinotevera chekurapa kuupenyu.

Tsvaga ramangwana rekusimudzira zvinodhaka neIphaase-Kuda mushonga wekunyepedzera wakakodzera zvishandiso zvekushandisa.