Miedzo isingafadzi? Iyo itsva vhezheni yein- vitro micronucleus test kit iri pano kuti ibatsire!

CHIKAMU 01. In-Vitro Micronucleus Test

Micronuclei machromatid akazara kana acentric fragments kana mhete machromosome anoramba ari mucytoplasm apo machromosome anogara achipinda mumwanasikana kuita nuclei mushure memitosis. Nekuda kwekuti zvidimbu izvi kana machromosomes haakwanise kupinda munucleus hombe patelophase, kana masero emwanasikana apinda muchikamu chinotevera, anobatana kuita nuclei diki kunze kwemukati mukuru uye kuita micronuclei. Nekujekeswa kwemaitiro ekugadzira, kukosha kwemicronuclei, kuenderera mberi kwekuvandudzwa kwenzira yekuona uye kukwana kwemaitiro ekuyedza, micronucleus test yakava imwe yenzira huru dzekuongorora shanduko. Inoshandiswa zvakanyanya kufanotaura njodzi yecarcinogenic, kuona aneuploidy inducers uye dzimwe njodzi dzemajini.

Iyo in-vitro micronucleus bvunzo inzira yekuongorora genotoxicity yekuona kugadzirwa kwemicronuclei mumasero emammalian mushure mekurapwa nechinhu chekuyedza. Yakanakira kutarisa kutsemuka kwechromosome uye aneuploidy yakanyudzwa mumaseru emitotic panguva / mushure mekuratidzwa kune chinhu chekuyedza. Kuenzaniswa nein-vivo bvunzo, iyo in- vitro micronucleus bvunzo iri nyore, inokurumidza, uye yakachipa. Mukuwedzera, hazvikanganisike nezvinhu zvakadai sekusiyana kwega pakati pemhuka dzekuedza. Sezvo in - vitro micronucleus bvunzo inogona kuona micronucleus reactions inokonzereswa nemamwe makemikari panguva yakaderera yekudzika nekunzwa kwakanyanya. Naizvozvo, yakashandiswa zvakanyanya mumunda weiyo genetic toxicology.


CHIKAMU 02. In vitro micronucleus test kit

Iyo IPHASE in-vitro micronucleus test kit inoshandisa masero eChinese Hamster Lung (CHL) seye test system. Masero eCHL anoratidzirwa kune chinhu chekuedza ne / pasina metabolic activation system uye anobatwa ne actin polymerization inhibitor cytochalasin B. Masero anobvumirwa kusvika kune avo akakodzera nguva yemasero e-binucleated, uye ipapo kukohwa, kugadzirirwa, uye kusvibiswa; ipapo mwero wemicronucleus wemasero akapedzisa mitosis imwe (binucleated masero) anoongororwa pasi pemaikorosikopu kuti aongorore kugona kwe mutagenic yechinhu chebvunzo. IPHASE kit inopa ese akakosha reagents uye maseru e in - vitro micronucleus yekuyedza. Sezvo ese makiti akapfuura akasimba emhando yekuyedzwa, iyo inogadzirwa mhedzisiro mhedzisiro ndeyechokwadi, yakavimbika uye inogoneka.

--Product Advantages --

1. Zvakanakira

Inochengetedza nguva yekukwezva S9 uye reagent kugadzirira,. Kit inogona kushandiswa zvakananga, ichipfupisa zvakanyanya kutenderera kwekuyedza.

2. Kururama

Chimwe nechimwe chikamu cheiyo reagent kit chakaiswa pasi pekuyedzwa kwemhando yepamusoro, saka mhedzisiro yekuyedza uchishandisa kititi ndeyechokwadi, yakavimbika uye inodhinda zvakanyanya.

3. Kugadzikana

Iyo kit yakagadzikana uye iri nyore kutakura uye kuchengeta.

4. Versatility

Yakasiyana-siyana mashandisirwo, anogona kushandiswa genetic toxicology kuongororwa kwechikafu, makemikari, mishonga yekuuraya zvipembenene, mishonga inouraya utachiona, zvinowedzera chikafu, zvekuzora, uye zvimwe zvakawanda.

Kuenzanisa kwekiti itsva uye yekare

IPHASE inotevera zviyero zvenyika uye nhungamiro ye in- vitro micronucleus bvunzo mundima dzakasiyana sekutungamira kwayo kwehunyanzvi. Zvakare, IPHASE inotora mhinduro yemutengi sechinangwa chayo chekugadzirisa kugadzirisa maumbirwo uye maitiro echigadzirwa uye yakabudirira kukwidziridza in- vitro micronucleus test kits kuti isangane nezvimwe zvinodiwa nevatengi kunyangwe mushure mekuenderera mberi kwekuongorora.

1. Product Composition

Giemsa staining reagents uye reagents anodiwa pakuita gadziriro akaverengerwa kuti zviite nyore uye zvinobudirira.

2. Methodology

Iyo kit protocol yakanyatso kutsanangurwa, pamwe nekubatanidzwa kweyedzo yekudzivirira uye zvimwe zvirimo kudzivirira zvikanganiso zvakajairika.

CHIKAMU 03. Related Products