Kenyelletso eaThe magnetic e sebedisang selefouno
Ho hlophisoa ha magnetic ho etsa mefuta ea sele (macs) ke theknoloji ea bohlokoa tšimong ea bioology ea sele ea sele ea selefouno le lipatlisiso tsa biomedical. E le mokhoa o matla oa ho hlophisa, Macs o etsa hore bafuputsi ba khetholle mefuta e khethehileng ea lisele tse tsoang ho baahi ba tierroge le likopo tsa bongaka. Nts'etsopele ho ntlafatsa ts'ebetso le ho hlophisoa ha sele, mokhoa o sebelisa lieta tsa magneties tse kopaneng le lisele tse tobileng.
Melao-motheo e mabapi le Theknoloji ea Macs
● Li-semelo tsa temo tsa mateanetic
Molao-motheo oa macs o ipapisitse le karohano ea makenete. Ts'ebetso ena e kenyelletsa ts'ebeliso ea likaroloana tsa makene, hangata Nano - Liraka tse imetsoeng li koaheloa ke li-antibodies, ho tlama li-conkers tse ikhethang tsa lisele. Ha motsoako oa mohlala o phalla ka kholomo ka holim'a matla a khoheli, makenete - Lisele tse sa ngolisoe li bolokiloe, ha li fetile lisele tse halikiloeng. Karohano ena e ikhethileng e fihlella ntle le ts'ebetso ea sele, e e etsa khetho e ntle bakeng sa baahi ba li-cell ba foufetseng.
● Karolo ea li-antibodies tse fapaneng tsa sele
Li-antibodies li bapala karolo ea bohlokoa ho boloi - ho hlophisa sele. Ba tsamaisana le litselana tse tobileng tsa litekete tsa makenete, netefatsa hore ke lisele tse lakatsehang feela tse arotsoeng. Tsiniki ena ke patsi bakeng sa ho fumana lintlha tse phahameng haholo -
Lisebelisoa tse sebelisitsoeng ka Macs
● Tlhaloso ea likholomo tsa MACS
Macs Colns Litšoaneleho tsena li behiloe ka har'a lebala la masene, li lumella boloi - lisele tse halikiloeng tse tla bolokiloeng. Mefuta e fapaneng ea leqephe e fumaneha, e fapana ka boholo le bophahamo ba ho amohela lintlha tse fapaneng tsa mohlala le linomoro tsa sele.
● Mefuta ea lieta tsa makenete
Katleho ea Macs e itšetleha haholo ka boleng ba mekhoa ea makenete e sebelisitsoeng. Libata tsena li enjene ka thepa e fapaneng le thepa e fapaneng ho lumellana le lits'ebeliso tse fapaneng, ho kenyelletsa boholo ba linaoa, matla a bolokolohi le lisebelisoa tsa ho koahela. Ho khetha makenete e phahameng - Make e Bohlokoa -
Mokhoa oa magnetic - Ho hlophisa selefouno
● Mohato - - - - mohato oa mohato
Ts'ebetso ea macs e hlakile ebile e hloka ho nepahala. E qala ka mangolo a thekiso ea lisele, moo lisele li kentsoeng ka mabenyane a makenete ea makenete e kopaneng le li-antibodies tse khethehileng. Lisele tse halikiloeng li kenngoa kholomong ea macs tlasa feme ea makenete. Batho bao e seng - lisele tsa sepheo pele, le ka mor'a ho tlosa kholomo tšimong ea maginetic, lisele tsa sepheo li bokelloa. Mokhoa ona, ha o etsoa ka nepo, ho fella ka chai e phahameng ea lisele tsa sepheo se hloekileng.
● Kemiso ea mohlala
Boitokisetso bo nepahetseng ba sampole ho bohlokoa bakeng sa macs a atlehileng. Sena se kenyelletsa ho netefatsa bolekane - Lits'oants'o tsa sele, 'me li tlosa li-aggGregen tsa sele, le ho fetola libaka tsa li-cell tsa sele. Mekhoa e tšoarang e tlameha ho fokotsa khatello ea lijalo le ho sebetsana le eona, haholo bakeng sa mefuta e fapaneng ea sele ea stem.
Likopo tsa Macs tsa Macs Patlisiso le Bongaka
● Sebelisa Patlisisong ea Kankere
Macs e sebelisoa haholo lipatlisisong tsa kankere hore li arole lisele tsa kankere tse sa tloaelehang tse tsoang ho limo tsa mali, ho thusa ho fumana tlhahlobo ea kalafo ea mali. Ka ho fana ka li-sampole tse phahameng tsa Presh, Macs e ntlafatsa ho nepahala ha lihlahlobo tse tlase, tse kang phallo ea lipalesa le linomoro tsa moleng.
● Likopo ho kalafo ea stem
Bokhoni ba ho khetholla batho ba bangata ba stem ba etsa hore Macs ba bohlokoa haholo kalafong ea bocha. E thusa ho tsosetsoa ha lisele tsa Steme ho hloka kalafo, ho netefatsa hore kalafo e bolokehile ebile e sebetsa.
Melemo ea macs ho feta mekhoa e meng
● Lintho tse phahameng le katleho
Ha ho bapisoa le mekhoa e meng ea ho hlophisa meepo ea sele, e fana ka maikutlo a sa laoleheng le katleho. Ts'ebeliso ea li-antibodies tse khethehileng li tiisa hore feela lisele tsa sepheo feela li arotsoe, ho fokotsa kotsi ea tšilafalo e sa batleheng le ho ntlafatsa liteko tsa liteko.
● Sele e bonolo e sebetsa
Macs e tsebahala ka selefou ea eona e bonolo, ea bohlokoa bakeng sa ho boloka sele ea botšepehi le ts'ebetso. Ho fapana le mekhoa e thata, ho sebetsa lisele ka mokhoa o bolokang puso ea bona ea puso, e etsa hore ba etse lipatlisiso tse ling kapa tšebeliso ea kalafo.
Meeli le liphephetso tsa Macs
● Monyetla oa hore u se ke oa khetha
Phephetso e le 'ngoe le mac ke monyetla oa ho ba batho ba se nang bolulo, moo lieta li sehokahanang le lisele tse sa lebelloang. Sena se ka fokotsoa ka ho sebelisa litlaleho tse phahameng tsa boleng le ho etsotella liketsahalong tsa antibod.
● Mehopolo ea litšenyehelo
Le ha ho sebetsa hantle haholo, macs ho ka ba theko e phahameng haholo ho feta mekhoa e meng, haholo-holo ka lebaka la litšenyehelo tsa lieta tsa makenete le lisebelisoa tse ikhethang. Bafuputsi ba tlameha ho rarolla litšenyehelo tsena khahlanong le melemo ea holimo - bohloeki.
Liphetoho tsa morao tjena ho Macs Technology
● Litaba tse hlophisitsoeng ka boqapi ba li-magnetic
Tsoelo-pele ea morao-rao ea mahlale a Beaad e ntlafalitse ts'ebetso ea macs. Meetso e mecha e fana ka matla a mabe a ntlafalitsoeng le ho tlamaka ho ananelang, ho lumella bohloeki bo boima le bo phahameng.
● Lipalo tse ntlafalitsoeng tsa ho hlophisa
Tsoelo-pele ea nts'etsopele ea Protocol e na le lits'ebetso tsa mas, fokotsa linako tsa ho hlophisa le ho ntlafatsa ts'ebetso. Lintlafatso tsena li etsa hore macs a fumanehe le ho a hohela mefuta e pharaletseng ea li-laboratori tse pharaletseng.
Papiso ea macs ka mekhoa e meng ea ho hlophisa
● Fruorescence - Morao o hlophisitsoeng oa selefouno (fachs) vs macs macs
Le ha litonthung ke mokhoa o mong o tloaelehileng oa ho hlophisa, Macs o fana ka melemo e kang lisebelisoa tse bobebe le ho rarahalla hanyane ka hanyane. Ho fapana le litoropo tse lekang laser, ho sebelisa chelete e thata -
● Litsela le mathata a e mong le e mong
Mokhoa o mong le o mong oa ho khetha o na le melemo ea eona le lits'oants'o tsa eona. Merero ea litoropo e fana ka tlhaiso-leseling e qaqileng ea Prohenoty empa e theko e boima haholo ebile e theko e tlase - ho ja. Leha ho le joalo, Macs e fana ka sekhahla, litšenyehelo - Setlhareiking e sebetsang ka litlhokahalo tse sa sebetseng tsa teknoloji, e loketseng lits'ebetso tsa kemiso.
Mehopolo ea bokamoso le liketsahalo tse ka khonehang
● Makhoakhoa a ho hlophisa sele
Ha tlhoko ea bongaka ea ho phela e hola, mahlale a ho hlophisa likotlo tse kang Mac o tla tsoela pele ho fetola. Nts'etsopele ea nako e tlang e ka kenyelletsa ho kenella, ho hokahana le ho kopana le mekhoa e meng ea tlhahlobo ea tlhahlobo ea almanaka.
● Ho ntlafatsa mahlale a Macs Technology
Ho ka etsahala boipiletso ka mokhoa o tsoelang pele theknoloji ea Beade le likotlo tsa kholomo e kanna ea ntlafatsa ts'ebetso ea MACS. Ho feta moo, ho kopanya li-wwostictics tsa data le biointostostostostatics li ka ntlafatsa khopiso e fumanoang ho tsoa ho li-cell tse hlophiloeng.
Sephetho
Makene - Mokhoa o hlahisitsoeng oa ho hlophisa oa sele o hlahella e le mokhoa oa ho ntlafatsa sebakeng sa phetohelo ea selefouno le biomedicine. Boholo ba eona bo phahameng, katleho le ho tsamaisa bonolo le ho sebetsana le bonolo ho li etsa khetho e ratoang ea ho khetholla mefuta e ikhethileng ea lijana tse fapaneng tsa lipatlisiso le likopo tsa bongaka. Ho khetha Phahameng - Makeno a Bohlokoa - Moetsi oa boleng bo sebetsang, fektheri, kapa morekisi o bohlokoa ho fihlela liphetho tse lekaneng le theknoloji ea mass. E le tsoelo-pele ea theknoloji, macs e tla tsoela pele ho bapala karolo ea bohlokoa ea ho etsa lipatlisiso le lits'ebetsong tsa kalafo ea boitšoaro.
●Iphase: Molekane oa hau ea tšepahalang ka lebaka la bo-ratoang
Li-kholo tse ka leboea ho Wales, Pennsylvania, Biosciens ke "ikhethang, nose, 'me norprise e phahameng - Phahameng. Khampani ea rona e ntlafatsa lipatlisiso, nts'etsopele, tlhahiso, thekiso le lits'ebeletso tsa mahlale tsa bahoepo ba koetliso ea bong bo ntlafalitsoeng. Ho na le tsebo e eketsehileng le takatso ea ho etsa lipatlisiso tsa saense lefatšeng, ho fana ka bafuputsi ba bohlokoa lefats'eng ka bophara, fana ka bafuputsi ba tšehetsang bafuputsi ba ho fihlela lipheo tsa bona tsa mahlale. Iphase e thehile meaho e mengata ea R & D e ka pholla Chaena, United States, Europe le Asia Bochabela. Joaloka moetapele ho ea ho ea ho -
Nako: 2024 - 26 - 26:41