Genotoxicity
Litlhahlobo tsa Genotoxicity ke liteko tsa in-vitro le in-vivo tse sebelisetsoang ho bona lintho tse bakang tšenyo ea lefutso ka ho toba kapa ka tsela e sa tobang ka mekhoa e fapaneng ea tšenyo ea DNA, e ka hlahang ka mokhoa oa phetoho ea liphatsa tsa lefutso le ho fetoha ha chromosomal. Litšenyehelo tsena lia tsoaloa 'me li kenya letsoho kholisong ea mekhahlelo e mengata ea lihlahala tse kotsi. Hobane ha ho tlhahlobo e le 'ngoe e ka bonang lipheletso tsohle tsa genotoxic, ts'ebetso ea tlhahlobo e tlameha ho sebelisa motsoako oa liteko tse fapaneng ho lekola ka botlalo kotsi e ka bang teng ea genotoxic ea ntho ea tlhahlobo.
E sebelisa lilemo tse mashome ho nts'etsopele ea morero oa lipatlisiso tsa genotoxicity le ts'ebetso e tsoelang pele, IPHASE e hlahisitse mefuta e fapaneng ea liteko tsa in-vitro genotoxicity: Ames, Mini-Ames. TK/HGPRT, Aberration ea Chromosomal, Micronucleus, Comet. Ho feta moo, likarolo tsa bohlokoa tse kang Liver S9 Activation System, Giemsa staining reagents le tsona li fanoa. Ha e le hantle, lihlahisoa tsena li etselitsoe ho nolofatsa mekhoa ea tlhahlobo ka ho felisa mokhoa o khathatsang oa ho itokisa le ho ntlafatsa ts'epahalo ea thuto ka litlhaloso tse hlophisitsoeng hantle tsa sehlahisoa ho hlola liphephetso litekong tsa in-vitro genotoxicity.