CGT Therapy - Lenntivirus - Koloi ea ho jarolla ka lisele tsa 'mele
Lefu la bongaka la 'mele la Itterna ke kalafo e nchafalitsoeng e ntlafatsa sesole sa' mele sa 'mele ho netefatsa le ho tlosa lisele tsa kankere. Litso tsa Bohlokoa li kenyelletsa cytokine - Thepa ea Cell Cell Therapy, T - Thepa ea Lisele le Koloi ea Cels. Koloi ea Likoloi e kenyelletsa lisele tsa TAM ho hlahisa li-antigen Antigen lisele tse tsoang ka mokhoa o hlakileng, tse bonts'ang katleho ea hlapollo e kang ea Humto, le lymphoma.
Mantsoe a bohlokoa: Koloi - T, Lenntiviral, Lentiviral Vector, TraccEc
Ho hlophisoa ha koloi - THE CELLDIY
Ka kakaretso, mehato ea bohlokoa ea ho lokisa koloi -
Mohloli: Dana - Setsi sa mofets'e
- 1.Soung (T - Ho itšehla thajana)
Mohato oa pele oa ho lokisa la koloi - lisele tsa T li khetholla T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T TLE - lisele tse tsoang lisele tse tšoeu tsa mali maling a mokuli. Mekhoa e kang ea ho arohana ha bead ea 'mele kapa ho phalla ka mokhoa o hlakileng hangata e sebelisoa ho fetisa CD3 + - Lisele tse tsoang maling. Ho etsa bonnete ba bohloeki ba sele, ts'ebetso ea ho khetha e hloka ho ba hantle haholo, e netefatsa hore palo e lekaneng - Lisele li fumanoa.
- 2.Stimulation (t - ts'ebetso ea sele))
Lisele tse ntšitsoeng li kenngoa ka har'a vitro, hangata li sebelisa aCD3 / CD28 T - Lieta tsa Ts'ebetso / Kitty. Lisele tsa TS e sebetsang li kenya letsoho le mafolofolo, li li lokisetsa phetohelo ea 'mino. Ka ts'ebetso ena, ts'ebetso ea well e ntlafatsoe, e kenya letsoho ho fumana liphallelo tsa liphatsa tsa lefutso le kalafo.
- 3.Trans scrant (mofuta oa mofuta oa mofuta)
Setsi sa TV ea TRUCHANED TERCO CONTO CONTO CONSE TERCHING COCH Antigen Record Antigen (Koloi). Ts'ebetso ena hangata e sebelisoaLenntiviral VectorHo tsebisa mefuta ea koloi ka lisele tsa T. Lenntivirus ke sesebelisoa sa Tranction sa Transition, ka monyetla oa ho kopanya mokhanni oa sepheo (joalo ka koloi ea koloi) ka selikalikoe sa lisele. Ka ho tšoaetsa lisele tsa TST le ho tšoaetsa likoloi tsa koloi ho ea Cell DNA, Lendinti a thusa lisele tsa TLEG ho hlahisa likoloi tse telele - Koloi ea koloi e kenyelletsa sekhechana se le seng sa Chain (scfv) ea antigart ea Tum ho amohela karabelo ea ho itšireletsa le ho kenya letsoho libaka tsa botsitso tsa lisenthing tsa T. Joalokaha ho bontšitsoe Setšoantšong sa 2. Phetoho ea lepono e nang le litšobotsi tse phahameng le botsitso, e le hore mofuta oa koloi o ka hlahisoa ka liserekisi tse telele.
Mohloli: Likoloi tsa Singapore - t Cell kalafo
- 4.EPELING (CONY SELLIFATER)
Kamora hore tlelaetso, koloi - lisele tsa T-TA li kena mothating oa ho qala, moo litšobotsi tse kangIL - 2li eketsoa ho khothaletsa ho eketseha ha Cell. Morero oa ts'ebetso ena ke ho netefatsa hore palo e lekaneng ea koloi - Lisele tsa T li fumaneha bakeng sa ho kenngoa ha nako ea mokuli. Ts'ebetso ea ho qala e tlameha ho etsoa tlasa maemo a sa lutseng ho netefatsa boleng ba sele le bongata.
- Taolo ea 5.Qity (QC)
- Pele u emisa ho ba mokuli, taolo ea boleng e bohlokoa nakong ea ts'ebetso ea tokiso. Koloi e Lokisitsoeng - Lisele tsa T tsa Tetsa bonnete ba bohloeki ba bona, tšebetso, katleho ea phekolo, le ho latela litekanyetso tsa kalafo. Ntle le moo, ho fumana tlhahlobo ea tšilafalo ea seli kapa karabelo e mpe ho hlokahala ho netefatsa katleho ea lisele ka mor'a ho hlakoloa ho buluoe.
IHo tsamaisana le ho fetisetsa tšoaetso ho lisele tsa 'muso
Mahlale a ho fetisa ha mahlale a mantlha a ho itšireletsa mafung a 'mele, haholo-holo bakeng sa ho hlophisa boenjiniere ba mokha. Baitlami ba Lenntiviral, ba fetotsoeng ke HIV - Li ka tšoaetsa lisentiping le tseo e seng tsa ho arola lisele, 'me polokeho ea bona e ntlafalitsoe ka ho fetola mefuta ea boleng. Barekisi bana ba se hangata ba sebelisoa kalafo ea liphallelo, ho hlophisa mokhanni, le ho tsamaisa buka ea biology ho etsa mosebetsi oa bona.
Mohloli: Obish.com/product/ PUBUduct/ Sepheo sa Setšoantšo sa LetntiviRund
Ho Tlisoa ka Tsela ea Gene
Lentiviral Vector e ka fana ka maikutlo a lefutso liphaefo, joalo ka liphasele tsa ho tloha le lisele tsa ho senyeha, li tiisa hore mokhanni oa koloi le ho eketseha ha sele. Ena e phahameng - bokhoni ba Transalty "bo sebetsa ke ntho ea bohlokoa bakeng sa katleho ea thibelo ea thibelo.
2.lolower internononicity
Ha ho bapisoa le lijana tse ling tsa vaerase, lentibuuse e na le ho ipeha ha linoko tse tlase. Ka lebaka leo, ha likhopolo li sebelisoa ho tsamaisa lisele tsa 'li-itširese ea' mele, sesole sa 'mele sa mokuli se hlahisa karabelo ea ho itšireletsa mafung a vaerase. Sena se thusa ho fokotsa karabelo e mpe, haholo-holo ka nako e telele - batho ba pholohang ha ba qeta ho khesoa ha mmele o feteletseng ba ho fokola.
3.Ha Tenderwaba ho lisele tsa 'mele
Lentiviral Vector e khona ho hlahisa mefuta e fapaneng ea lisele tse sa amaneng le lisele tsa ho itšireletsa mafung,haholo-holo lisele le lisele tsa NK. Ka ho Tlisoa ho mantlha, lisele tsa'holimo li ka fumana tumor - Bokhoni bo Nepahetseng, ka ho etsa joalo ba khothaletsa bokhoni ba bona ba ho sheba le ho bolaea lisele tsa tumor.
4.precining ea lisele tse fetisitsoeng bakeng sa ho amoheloa ha lisele
Ha batopurapy,e fetisetsoa lisele tsa fensetereMabapi le lisele tsa 'mele tseo, kamora ho tlisoa, ho bontša koloi' me u antis anti - Ts'ebetso ea TUMOR. Baitlami ba Lenntiviral ba ka fana ka koloi ea koloi e hahang ka har'a lisele tsena tsa femente, e ba nolofalletsa ho lemoha le lisele tsa tumor.Lisele tsa sepheoke lisele tsa tumor tse khetholloang le tse sentsoeng ke lisele tsena tsa 'mele. Ka ho Tlisoa ka Matlabollo, lisele tsa 'boloi li ka ntlafatsa tumelo ea bona ho tsebahalang, ka ho etsa joalo, ho ntlafatsa maqhubu a hlapil.
Moelelong ona, Iphase, Moetapele oa Boikemisetso ba VIDR, o ntlafalitse mochini oa bangoli oa lekhetho le ho ntlafatsa sekhahla sa phetisetso ea lefu la ho tsitsipana. Lihlahisoa tsena li fana ka tharollo ea ho emisa bareki.
Iphase LetntirirusPRoction
Kit ea Iphase LetntiRuse na le mathata ohle a bohlokoa a hlokahalangPate ea Lenntivirus, ea ho nolofatsa boemo ba liteko le ho boloka nako le boiteko. Kena ena e kenyeletsa:
- Lentervirus Packaar Plasmid Remix
- Tloaelo ea Thrients
- EGFP Plasmid
- Iphase Letntirirus ea Lulaten ea Ikhunya
Ke kmphutlo ena e totobatsang teko! Ha ho na tlhoko ea litokisetso tse rarahaneng, liphutheloana tsa lendntintirus li ka phethoa ka nepo ka latela litaelo tse kenyelelitsoeng.Melemo e ikhethang ea kit e kenyelletsa nako e khuts'oane ea ho becha, li-char tsa vaerale tse phahameng, le ts'ebetso e bonolo, e etsa hore e be e loketseng liphutheloana tsa liprothekeng. Letoto le leng le leng le le leng le le leng le le leng la boog le thata le ntlafatsang litholoana tse nepahetseng le tse tsitsitseng haholo, ka tsela ea ho ba le matla a ho iphelisa.
Ho feta moo, ho thusa bareki ho boloka litšenyehelo, Iphase le tsona li ntlafalitsetse 'me li hlahisitse mokhoa o susumetsang oa lekhetho, a fana ka tharollo e potlakileng le e bonolo.Ka ho kopanya lepotlapotla ho ile ha ba matlafalitsoe ke mokhoa oa ho itlhoekisa, o lateloa ke ho intša le ho kenella ka nakoana a sebelisa centrifuge e tloaelehileng. Ts'ebetso ena ha e hloke morero oa ultrastralifuge, e e etsang e bonolo ebile e le litšenyehelo - khetho e sebetsang bakeng sa basebelisi ba laboratoring e ngata.
Mahloriso a potlakilengPhepelo ea mahloriso e phethoa ka hora e le 'ngoe feela.Ho eketseha ha leshome: Khopo ena ho ka eketsa vector ea vaerase ka 10 - makhetlo a 100, ha a ntse a nyenyefatsa lintho tse bonahalang, a e tsebisa -
Ho bonolo ho e sebetsa: Tsamaiso e hlakile, e hloka lisebelisoa tse rarahaneng kapa tse atolositsoeng ho incubation ea mosebetsi o boima.
Ka bokhutšoanyane, Iphase Anchuruant ea Iphase Ha e ntlafatse haholo phetohelo ea phekolo ea phekolo e ngata empa e fana ka e phahameng - Ke sehlahisoa sa bohlokoa bakeng sa liteko tse tloaelehileng tsa liteko, lipatlisiso tsa pele le libaka tse ling tsa kopo.
|
Ntho Che. |
Lebitso |
Boholo ba yuniti |
|
074001.11 |
Iphase Letntirirus ea Lulaten ea Ikhunya |
50 ml |
|
074001.12 |
Iphase Letntirirus Packging Kit |
Teko ea 10 |
Ka kakaretso, elembonotherapy, haholo-holo koloi - Ka mekhoa e nepahetseng e kang selefouno, tranliction, katoloso, likhakanyo le taolo ea batho ba baholo bakeng sa bakuli.Ho Tlisoa ha motheo, e le theknoloji ea mantlha, e bapala karolo ea mafu a bohlokoa ho lokiseng koloi ea hau -Ka tsoelo-pele ea Mangolong a sa khaotseng, ationnonotherapy e na le bokhoni ba ho fana ka mekhoa ea phekolo e ncha le bakuli ba eketsehileng, e fanang ka boleng bo boholo ba ho fana. Nakong e tlang, ho lebeletsoe ho tlisa phetohelo ea phekolo ka tšepo ea hore bakuli ba nang le mofetše.
Ho fihlela litlhoko tsa tsamaiso, polelo le lipatlisiso tsa maloetse, Iphase e fana ka li-lagins tsa letinter, lentivirus tsa mahloriso. Li-lectisuse tsena tsa tracer li tsamaisoa le protheine e botala ba fluorescent, prothein e khubelu ea fluorescent, e nolofalletsang ho latela lisele tsa sepheo ho vitro le vivo.
Ntle le moo, Iphase e ka fana ka tse peli pele - E pakile letlapa la Tracer e pakiloeng - GFP & Luciaranry le Luciarry le Luciarry le Luciarry le Luciarry le Luciarry le Luciferase. Barekisi bana ba ka khethoa kapa ba kopantsoe ho latela litlhoko tsa liteko, ba ntse ba ntlafatsa litsebo le ho holisa katleho bakeng sa Seal -
|
Ntho Che. |
Lebitso |
Boholo ba yuniti |
|
074001.13 |
Iphase EGFP - Luciarata Letinnti |
50 μl zalis, 1E8 tu / ml |
|
074001.14 |
Iphase McERRY - Luciferase Letin |
50 μl zalis, 1E8 tu / ml |
|
074001.15 |
Iphase EGFP - Handferase - Puro Lentivirus |
50 μl zalis, 1E8 tu / ml |
|
074001.16 |
Iphase McERRY - Luciarata - Puro Lentivirus |
50 μl zalis, 1E8 tu / ml |
IphaseIMmnonotherapyRE na lePRoction
Ntle le lentervorus - lihlahisoa tse amanang le tsona tse sebelisoang ka koloing, e ne e le moetapele oa ho etsa lipatlisiso ka cgt (sele le meqolo ea Gene. Iphase e tsoetsoe 'me e hlahisitse litlolo le li-pbmcs (lisele tsa moriana tsa mohloa tsa mohloa tsa mohloa tsa mohloa tsa mohloa tsa mohloa tsa mohloa tsa mohloa tsa mohloa tsa mohloa oa litloholo tsa markapherasus, hammoho le imts tsa ho itšireletsa mafung, ho ts'ehetsa nts'etsopele e potlakileng ea ho itšireletsa.
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Lebitso |
Mokhoa oa ho hlophisa |
Boholo ba yuniti |
|
Leukocyte ea motho |
Leukaphebisos |
Limilione tse 5 |
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Motho/Litšoene/Ntja (Begle)/Rat (Sprague - Dawley)/Mouse/Minipig (Bama)/Rabbit (New Zealand White)/ Katse /Guinea pigLisele tsa Mali oa Mali oa Mollo oa Mollo (PBMC) |
Karohano e felletseng ea mali |
5/10/20 |
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Iphase monna oa IS3 + Ts |
Khetho e mpe |
5/20 |
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Iphase Human CD4 + T lisele |
Khetho e mpe |
5/20 |
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Iphase Cd8 + t lisele |
Khetho e mpe |
5/20 |
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Iphase monna oa motho ea nang le lefu la kelello + lisele |
Khetho e mpe |
2/5 milione |
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Iphase oa persipheral madi a cd19 + b lisele |
Khetho e mpe |
2/5 milione |
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Iphase motho oa motho ea nang le moea oa Iphase Cd56 + lisele tsa NK |
Khetho e mpe |
2/5 milione |
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Iphase motho oa motho oa mofuta oa madi cd34 + lisele |
Khetho e mpe |
Limilione tse 100 |
|
Iphase oa motho ea nang le lisele tsa mali |
CD14 + ho kenella |
1.5 milione |
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Iphase motho oa motho ea phelang oa mali |
CD14 + ho kenella |
1.5 milione |
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Motho / monkey / dob / mouse / mouse / pig / pig / mphebi (4% / 2%) |
Ho tloha ho 5 ml ea mali a felletseng |
100 ml (4%) 100 ml (2%) |
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Iphase mouse spleen cd8 + t lisele |
Khetho e mpe |
0.5 / 1/5 milione |
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Iphase CBMC |
/ |
Milione |
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Iphase oa persipheral madi a cd4 + t lisele |
/ |
Milione |
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Iphase oa persipheral madi a cd8 + t lisele |
/ |
Milione |
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Iphase monna oa motho ea nang le lefu la kelello + lisele |
/ |
Milione |
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Iphase oa persipheral madi a cd19 + b lisele |
/ |
Milione |
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Iphase motho oa motho oa mofuta oa madi cd34 + lisele |
/ |
Milione |
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Iphase oa persipheral madi oa madi cd36 + lisele |
/ |
Milione |
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Iphase motho oa motho ea nang le moea oa Iphase Cd56 + lisele tsa NK |
/ |
Milione |
|
Iphase Cell Medium |
/ |
10/30 ml |
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Iphase PBMC SEKHA - Tloaelo ea MAHALA ea Setsoalle ea mahala |
/ |
50/100 ml |
|
Motho / monkey |
Karohano e felletseng ea mali |
Ho fihla ho 100 ml ea mali a felletseng |
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Mouse / mouse cd3 + t lisese kit |
Khetho e ntle / khetho e ntle ea barekisi Khetho e mpe / khetho e sa sebetseng |
10/20/200 Teko |
|
Motho / mouse cd4 + Ts hale Seperation kit |
Khetho e ntle / khetho e ntle ea barekisi Khetho e mpe / khetho e sa sebetseng |
10/20/200 Teko |
|
Mouse / mouse cd8 + t lisese kit |
Khetho e ntle / khetho e ntle ea barekisi Khetho e mpe / khetho e sa sebetseng |
10/20/200 Teko |
|
Human / Monkey / Mouse CD14 + Lisele tsa Seperation Kit |
Khetho e ntle / khetho e ntle ea barekisi Khetho e mpe / khetho e sa sebetseng |
10/20/200 Teko |
|
Motho oa motho / mouse cd19 + b hanyetsa lisese |
Khetho e ntle |
10/20/200 Teko |
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Mouse / mouse cd56 + lisese Setsi sa Seperation Kit |
Khetho e ntle / likhetho tse mpe |
10/20/200 Teko |
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Sebaka sa motho / monkey / mouses / mouse Red |
Karohano e felletseng ea mali |
Ho fihla ho 100 ml ea mali a felletseng |
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Mong'a motho / mouse cd3 / cd28 t lisentsi tsa ts'ebetso / li-bead tsa katoloso |
/ |
20/100 Milione |
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Motho oa motho / mouse cd3 / cd28 t lisenthing tsa ts'ebetso / li-kits tsa katoloso |
/ |
20/100 Milione |
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Motho oa motho / mouse cd3 |
/ |
20/100 Milione |
Lihlahisoa tsa Iphaese li fana ka melemo e latelang, 'meSetifikeiti sa ho sekaseka (COA)netefalitsoe ke Iphase e fumaneha bakeng sa sehlopha se seng le se seng.
Tšireletseho
Lihlahisoa tsa Iphaese li entsoe ka manonyeletso a phetseng hantle pele - Ho hlahlojoa pele, HIV - 1/2, Sylilis).
Ho latela
Iphase e fana ka tumello tse boleloang e fanoa ke bafani, ka netefatso e hlakileng le e hlakileng ea mohloli.
Bohlale
Lihlahisoa tse fanoang ke Iphase, li fumanoe ka leukaphesus, li sebetsoa ke litsebi tse koetlisitsoeng. Each batch is accompanied by a corresponding COA, and the products are transported under a strict cold chain to ensure safety, rapid delivery, and quality assurance.
Tšebeletso ea bareki
Iphase e fana ka boemo bo phahameng - Ka mor'a - Tšebeletso ea thekiso, e netefatsa boiphihlelo bo bonolo mosebetsing oa ho ahloloa ho pholletsa le liteko.
Nako ea poso: 2025 - 2025 - 02 - 18: 17:52