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Introduction to mRNA drugs Messenger RNA (mRNA) is a sequence of nucleotides that encodes a protein, and in the cytoplasm is able to use organelles to express the encoded protein. mRNA drugs are chemi
Antibody-Drug Conjugate (ADC) is a relatively new type of biotechnology drug which couples small molecule therapeutic compounds to targeting antibodies/antibody fragment by linkers.
How to Prepare Slides for Comet Assay
The comet assay, also known as single-cell gel electrophoresis, is a sensitive and versatile technique for quantifying DNA damage in individual cells. Preparing h
Introduction to Tritosomes
● Definition and Significance
Tritosomes are specialized subcellular structures involved in various cellular processes, particularly in the regulation of metabolic pathways
The in vivo alkaline comet assay has been increasingly used in the genotoxicity evaluation of compounds. ICH S2(R1) has included the liver comet assay as the 2nd in vivo test for tissues/endpoints; an
Introduction to Liver Microsomes
Microsomes are small vesicular fragments derived from the endoplasmic reticulum and are found within liver cells (hepatocytes). They play a crucial role in various bio
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