Technical Notes
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Advancements in Bioanalysis: The Role of LC-MS/MS in Ophthalmic Drug Development and Aqueous and Vitreous Humor Studies
IPHASE Products Product Name Specification IPHASE Human Aqueous Fluid 1mL IPHASE Monkey(Cynomolgus) Aqueous Fluid,Male 1mL IPHASE Rabbit(New Zealand White) Aqueous Fluid,Male 1Read more -
Comparative Analysis of Peripheral Blood Mononuclear Cells (PBMCs): Across Species Applications in Immunology and Therapeutic Research
IPHASE Products Product Name Specification IPHASE Monkey(Cynomolgus) PBMC,Frozen 5million IPHASE Monkey(Rhesus) PBMC,Frozen 5million IPHASE Dog(Beagle) PBMC,Frozen 5millionRead more -
In Vitro Evaluation of In Vitro Drug Transporter: Exploring the Roles of ABC Vesicles and SLC Transporter Cells
Keywords: ATP-binding cassette(ABC), ABC Transporter, SLC Transporter, Membrane Vesicle, MDR1(P-gp), BSEP, BCRP, MATE1, MATE2-K, OAT1, OATP1B1, MDCK II, Caco-2, Transporter Inhibition, Transporter SubRead more -
Lysosomal Stability: A Key Factor in ADC Linker Performance and siRNA Delivery for Enhanced Therapeutic Efficacy
Keywords: ADC linker, Payload release, liver lysosome, lysosomal stability, lysosome catabolism, Cathepsin B, DS8201a, GGFG-DxD, GalNAc‑siRNA, siRNA Delivery, siRNA Escape, Hepatocyte Lysosomes, Tritosome, Lysosomal Acid PhosphataseRead more -
N-Nitrosamines: An Enhanced Ames Test with Hamster liver S9
Keywords: N-Nitrosamines, NDSRIs, OECD 471, Enhanced Ames test, Hamster liver S9, Cytochrome P450 enzymes, Mutation Test IPHASE Products Product Name Specification IPHASEGolden Syrian HamstRead more -
Lysosomes (Tritosomes):A predictive in vitro test system for catabolism or lysosomal stability studies
IPHASE Products Item No. Product Name Specification 0151A1.03 IPHASE Human Liver Lysosomes,Mixed Gender 250μL,2mg/mL 0151B1.01 IPHASE Monkey(Cynomolgus) Liver Lysosomes,MaleRead more -
Lysosomes, the organs of cellular self-digestion
With the continuous development of biotechnology, the development of targeted antitumor drugs such as small molecule compounds, oligonucleotides and biologics has made rapid progress, among which siRNRead more