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The in vivo alkaline comet assay has been increasingly used in the genotoxicity evaluation of compounds. ICH S2(R1) has included the liver comet assay as the 2nd in vivo test for tissues/endpoints; an
● Introduction to chromosome aberration tests
Chromosome aberration tests are crucial tools in genetic research and clinical diagnostics. These tests are designed to identify and characterize structur
Introduction: Importance of Sprague Dawley Rats in Research
Sprague Dawley rats have become an integral part of scientific research due to their unique characteristics and versatility in various expe
Since the drug metabolizing enzyme activities gradually decrease with the prolongation of in vitro incubation time, traditional in vitro metabolism models have limitations such as short incubation tim
Introduction to Tritosomes
● Definition and Significance
Tritosomes are specialized subcellular structures involved in various cellular processes, particularly in the regulation of metabolic pathways
The isolation of Peripheral Blood Mononuclear Cells (PBMC) is a crucial technique in biomedical research and clinical applications. These cells include lymphocytes (e.g., T cells, B cells, NK cells) a
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