Me ake jawo s9?

Gabatarwa zuwaJawo s9

Induted S9 shi ne hanta - An samo enzyme Fasali da aka saba amfani dashi a cikin guba da bincike na biochemical. Ana shirya shi ta hanyar sa hanta hanta a cikin dabbobi, kamar beraye ko hamsters, tare da farmuse 1254, phenoblavone, ko Β - Wannan juzu'i yana da mahimmanci a cikin binciken Vitro, musamman a cikin kunnawa a cikin rayuwa, kamar yadda yake auren metabolicsm na Xenobiotism na Xenobiotics a jikin mutum.

A matsayin babban mai samar da ingantattun reciolatus,Ilimin lissafiKwarewa a cikin bincike, ci gaba, samarwa, da rarraba babban - rectionari kimiyya mai inganci, gami da jawo s9. Hedkwen a Arewa, Pennsylvania na Arewa, ilimin IMPUSE ya kafa wurare da yawa na R & D da yawa, da Amurka, Turai, da kasashen gabashin Asiya. Manufarmu ita ce tallafin masu bincike a duniya a cikin ƙoƙarin su na kimiyya, suna ba da damar zuwa sama don hanzarta binciken ƙwayoyin cuta da kuma karatun ƙwayoyin cuta.

Ta yaya aka shirya S9?

An kirkiro S9 an samar da shi ta hanyar rijiyar -

1. Ingantaccen Induction: Dabbobi (yawanci rodents) ana bi da su da enzyme - suna haifar da mahaɗan enzyme kamar Atclor 1254 don haɓaka ayyukan P450 na enzyme.
2. Hadakar han hanta: Bayan shigowar, kyafaffen hanta sun girbe kuma an yi homogenized.
3. Centrifugation da karuwa: An cire hanta da hadewar herogenifular don ware murabba'i na S9, wanda ya ƙunshi nau'ikan enzymes na rayuwa.
4. Ikon inganci da ajiya: Samfurin ƙarshe ya yi ƙoƙari sosai don tabbatar da ingantaccen aiki mafi kyau kafin a shirya shi kuma an adana shi a ƙananan yanayin zafi don kula da kwanciyar hankali don kula da kwanciyar hankali don kula da zaman lafiya don kula da kwanciyar hankali don kula da kwanciyar hankali don kula da kwanciyar hankali don kula da kwanciyar hankali don kula da kwanciyar hankali don kula da kwanciyar hankali.

Aikace-aikace na jawo S9

Jawo S9 yana da aikace-aikacen aikace-aikace daban daban daban-daban na kimiyya:

• Karatun metabolism na kwayoyi: Anyi amfani da su don bincika yadda ake motsa magunguna a jiki.
• Gwajin mutonajin: Yana taka muhimmiyar rawa a cikinBayyanawar Ames, inda ya taimaka wajen gano mahaɗan mutarci ta hanyar aikin simulatological.
• Carcinnogenicity da kuma rashin cancantar guba: Taimaka wajen tantance carcinogens da toxictants a cikin sunadarai.
• Kimantawa muhalli da kuma kimantawa: Taimaka wajen tantance amincin sunadarai da kuma gurbata muhalli.

Biossenan ilimin IPHAMES yana samar da babbar - tsarkakakku, high - aiki da aka jawo S9 cromtions, kawo masu bincike don cimma sakamako mai ingantaccen kuma ingantaccen sakamako a cikin waɗannan karatun.

Hanyar aiwatar da aikin da aka sanya s9

Sanarwa S9 da farko suna aiki ta hanyar:

• Lokaci na ITHANM: Cytochrropom P450 enzyme Syet na oxidizes, yana raguwa, ko hydrelyzes Xenobiotics, yana sa su ba su da aiki.
• Lokaci II Metabolism: Concugation halayen (misali, glucuronIDation, sulfation) inganta ƙididdigar ruwa don sauƙin tafiya. Ta hanyar kwaikwayon wadannan hanyoyin wucewa na rayuwa, jawo S9 yana da mahimmanci don nazarin hulɗar miyagun ƙwayoyi da masu maye.

Nau'in gutsuttsarin S9

Akwai nau'ikan fannoni daban-daban na S9 don takamaiman bukatun bincike:

• Haɓaka hanta S9: Kashi mafi yawanci ana amfani da shi a cikin Genotoxicity kuma ames gwaje-gwaje.
• Jawo hamster hanta s9: Yana ba da tsarin kunnawa na kunna lokaci don karatun kamawa.
• Aroclor - Haushi S9: Musamman jawo tare da farfolor 1254 don haɓaka ayyukan enzyme na rayuwa, ana amfani dashi sosai cikin kimantawa masu guba.

Abvantbuwan amfãni da kuma iyakance na amfani da S9

Abvantbuwan amfãni:

• Yana samar da ingantaccen tsarin don yin karatun metabolism a vitro.
• Ingantawa daidaito a cikin annabta magani - hulda da miyagun ƙwayoyi.
• Yana ba da izinin yarda da bukatun tsarin gudanarwa don kimantawa na aminci.

Iyakantarwa:

• Ba ya da cikakken sauƙin hadaddun hancin ɗan adam.
• Ayyukan Enzyme na iya bambanta dangane da shirye-shiryen shiri.
• Dole ne a kula da yanayin kwanciyar hankali da kayan ajiya.

Yadda za a zabi dama ya sanya s9 don bincikenka

Lokacin zabar S9, yi la'akari:

• Nau'in tushe: Bera ko Fors hanta hanta yana samar da bayanan martaba daban-daban na enzyme.
• Gudun wakilai: Aroclor 1254 da vs. Sauran bayanan shigarwar suna tasiri kan furcin Enzyme.
• Bukatun aikace-aikace: Amin Gwaji, metabolism miyagun ƙwayoyi, ko kuma abubuwan maye gurbinsu suna buƙatar takamaiman abubuwan haɗin enzyme.

A ilimin Ilimi, muna bayar da jagora da kuma warware hanyoyin don taimakawa masu bincike sun zaɓi abubuwan da suka fi dacewa da gwaje-gwajensu. Kayan samfuranmu sun yi tsayayyen iko don tabbatar da cewa babban aikin enzyme da daidaito.

Ƙarshe

Idan aka jawo s9 muhimmin kayan aiki a cikin guba, masana magunguna, da kuma binciken aminci na muhalli. Ta hanyar kwaikwayon kunnawa na rayuwa, yana taimaka masana kimiyya gano mutafagusic, carcinogenic, da masu guba. A matsayina na amintaccen mai ba da labari na kwayoyin halitta, ilimin IMPUSE ya himmatu wajen samar da babban - inganci, bincike - aji ya jawo s9 zuwa dakunan gwaje-gwaje a duniya.

Don ƙarin koyo game da samfuranmu na S9 ko sanya oda, ziyarci shafin yanar gizon mu ko tuntuɓar ƙungiyarmu a yau.