Ọrụ nkwekọrịta
A na-enye ọrụ nyocha nkwekọrịta dabere na anyịna vitro nana vivo ule nyiwe mepụtara n'ụlọ. Anyị na-ejikọta anyị pụrụ iche ihe ọmụma na nnyocha ngwaahịa mmepe na anyị ihe karịrị 10 afọ omume na ubi na-enye ahịa ọkachamara na ahaziri ọrụ. Họrọ site na Pọtụfoliyo ọrụ wee kparịta ndị ọkachamara anyị gbasara mkpa gị, ị ga-enweta ngwa ngwa anyị, ọkachamara na ọnụ ahịa - ọrụ dị irè.
Gel filtration chromatography
ion mgbanwe chromatography
Affinity ọcha
Selụ anụ mammali (CHO, HEK293)
Okwu na-agafe agafe
Baculovirus okwu
Antibodies neutralizing ọrụ
Nchọpụta mmụba cell/apoptosis
Nchọpụta cytokines
Mgbochi mgbochi antigen na ụmụ oke na oke bekee
Nyochaa ngwakọta cell na hybridoma subclones site na WB, ELISA, FACS
Usoro nke yinye dị arọ na nke ọkụ na ime mmadụ
Okwu na-agafe agafe
Nkwado site na njide assay, KD, cell-nnwale dabere
Mpụta na ịsachapụ karama Roller
Cryopreservation na cell bank
Anti- idiotype antibody development
Nyocha ELISA maka mmepe na nkwado PK na ADA
Nleta mmekọrịta site na Blitz
Nkọwa nke epitope site na ELISA na WB
Nnwale ike nke sitere na cell: mgbochi nke mmụba cell, ịgbalite kinase (phosphorylation WB), nzuzo SAA, CCL17 na CCL21 inductionna PBMC
iPhase Biosciences ga-aza ngwa ngwa maka mkpa gị ma mee ntụgharị ngwa ngwa yana nrụpụta ọrụ dị elu. Site n'ọtụtụ ọgwụ mgbochi na ụzọ ikewapụ mkpụrụ ndụ tozuru oke, anyị na-enye gị mkpụrụ ndụ achọrọ nwere nnukwu mma na oke.
Anyị na-enye a keukwuna vitro ọrụ nke A (absorption), D, (nhazi), M (metabolism), na E (excretion) na ụlọ ọrụ ọgwụ. Nnwale ADME anyị na-abịa n'ụdị dị iche iche iji dabara na nchọpụta ọgwụ dị iche iche na ọkwa mmepe.
• In vitro permeability
• Nnwale nkwụsi ike Plasma
• Njikọ protein Plasma
• In vitrometabolic kwụsie ike
• Nnwale mgbanwe mgbanwe nje (AMES)
• Na Vitro
Nnwale chromosomal nke anụ mammalian
• Na Vitro
Nnwale mkpụrụ ndụ ihe nketa mammalian
• Comet Assay
Ụlọ ọrụ bioanalytical anyị nwere steeti - nke - ngwa nka, gụnyere LC-MS/MS, GC-MS, ICP-MS iji zụlite ụzọ nyocha maka organic, inorganic (ọla), na ngwakọta gaseous na nlere ihe ndụ. Ọrụ nke nkwado usoro na nyocha na-emezu ihe GLP na GCP chọrọ.
Ntọala usoro
Usoro nkwado nke uche, linearity, kpọmkwem, nkenke, na izi ezi wdg.
Bio-ntụle nlele
