Genotoxicity
Nnwale Genotoxicity dị in- vitro na in- vivo ule ejiri chọpụta ihe ndị na-ebute mmebi mkpụrụ ndụ ihe nketa ozugbo ma ọ bụ na-apụtaghị ìhè site na usoro dị iche iche nke mmebi DNA, nke nwere ike ime n'ụdị mgbanwe mkpụrụ ndụ ihe nketa na chromosomal aberrations. Mbibi ndị a bụ ihe nketa ma na-enye aka na mmepe multistage nke ụbụrụ ọjọọ. N'ihi na ọ nweghị otu nyocha nwere ike ịchọpụta ihe njedebe genotoxic niile, usoro nleba anya ga-eji nchikota ule dị iche iche iji chọpụta nke ọma ihe ize ndụ genotoxic nke ihe nnwale.
N'iji ahụmịhe ọtụtụ iri afọ nke mmepe mmepe nyocha nke genotoxicity yana njikarịcha na-aga n'ihu, IPHASE ewepụtala ngwa nyocha dị iche iche in-vitro genotoxicity: Ames, Mini-Ames. TK/HGPRT, Chromosomal Aberration, Micronucleus, Comet. Ọzọkwa, a na-enyekwa ihe ndị dị mkpa dị ka Sistemụ Nrụ Ọrụ Imeju S9, Giemsa staining reagents. N'ezie, a haziri ngwaahịa ndị a iji kwalite usoro nnwale site na iwepụ usoro nkwadebe na-agwụ ike yana kwalite ntụkwasị obi ọmụmụ na nke ọma-nkọwapụta ngwaahịa nke ọma iji merie ihe ịma aka na in- vitro genotoxicity tests.