Daim ntawv cog lus Services
Cov kev pabcuam tshawb fawb tau cog lus yog muaj raws li pebhauv vitro thiabhauv vivo xeem platforms tsim nyob rau hauv tsev. Peb muab peb cov kev paub tshwj xeeb hauv kev tshawb fawb cov khoom tsim nrog peb ntau tshaj 10 xyoo kev xyaum hauv kev ua haujlwm los muab cov neeg siv khoom tshaj lij thiab cov kev pabcuam customized. Xaiv los ntawm kev pab cuam portfolio thiab sib tham nrog peb cov kws tshaj lij ntawm koj tus kheej xav tau, koj yuav tau txais peb cov kev pabcuam sai, kev tshaj lij thiab nqi - cov kev pabcuam zoo.
Gel filtration chromatography
Ion pauv chromatography
Affinity purification
Mammalian Cells (CHO, HEK293)
Transient Expression
Baculovirus kev nthuav qhia
Antibodies neutralizing kev ua haujlwm
Cell proliferation/apoptosis detection
Kev tshawb nrhiav cytokines
Kev txhaj tshuaj tiv thaiv kab mob hauv nas thiab luav
Cell fusion and hybridoma subclones screening by WB, ELISA, FACS
Heavy chain thiab light chain sequencing thiab humanization
Transient qhia
Kev lees paub los ntawm kev sib tw, KD, cell-raws li kev xeem
Roller fwj ntau lawm thiab purification
Cryopreservation thiab cell banking
Anti-idiotype antibody kev loj hlob
ELISA kev ntsuam xyuas rau PK thiab ADA txhim kho thiab siv tau
Kev ntsuas affinity los ntawm Blitz
Epitope characterization los ntawm ELISA thiab WB
Cell-based potency assays: inhibition of cell proliferation, kinase activation (phosphorylation WB), SAA secretion, CCL17 and CCL21 inductionhauv PBMC
iPhase Biosciences yuav teb sai sai rau koj cov kev xav tau thiab cog lus nrawm nrawm thiab ua haujlwm tau zoo. Nrog rau ntau yam ntawm cov tshuaj tiv thaiv kab mob thiab cov txheej txheem ntawm kev sib cais ntawm tes, peb muab koj cov hlwb uas xav tau nrog kev lees paub siab - zoo thiab ntau.
Peb muab kev qhiahauv vitro kev pab cuam ntawm A (absorption), D, (kev tso cai), M (metabolism), thiab E (excretion) rau cov tuam txhab tshuaj. Peb qhov kev ntsuam xyuas ADME tuaj nyob rau hauv ntau hom ntawv kom haum rau ntau yam kev tshawb nrhiav tshuaj thiab kev txhim kho theem.
• Hauv vitro permeability
• Kev ntsuam xyuas ntshav plasma
• Plasma protein khi
• Hauv vitrometabolic stability
• Bacterial reverse mutation test (AMES)
• Hauv Vitro
Mammalian Chromosomal Aberration Test
• Hauv Vitro
Mammalian Cell Gene Mutation Test
• Comet Assay
Peb lub chaw bioanalytical muaj lub xeev - ntawm - cov cuab yeej kos duab, suav nrog LC - MS / MS, GC - MS, ICP - MS los tsim cov txheej txheem tshuaj ntsuam xyuas cov organic, inorganic (hlau), thiab gaseous compound hauv cov qauv biologic. Kev ua ub no ntawm txoj kev validation thiab tsom xam raws li qhov yuav tsum tau ntawm GLP thiab GCP.
Txoj kev tsim
Txoj kev validation ntawm rhiab heev, linearity, tshwj xeeb, precision, thiab raug thiab lwm yam.
Bio-Sample tsom xam
