Ulo Afe IMPASASE IITILASIL KIT, enwe (Cynomolgus)

IPHASE Phase II Metabolic Stability Kit,Monkey(Cynomolgus)

IMPASASE IITILASIL KIT, enwe (Cynomolgus)

Nkọwa mkpụmkpụ:

Naturani Metabolism, nke a makwaara dị ka mmeghachi omume na-ezo, na-ezo aka na mmeghachi omume nke obere motecules site na mbelata ihe na-egbu egbu, na-eduga na mbelata ihe na-egbu egbu, ọrụ, ma ọ bụ polarity nke prodrucs. Na oge nke II metabolism, mmeghachi omume kachasị na-akpali akpali, nke ndị Uridine Difhosphate glucurphate na prodrug site na nnyefe nke glucurnyl site na minit. Glucuronide kpụrụ mmiri na-abawanye ụba mmiri - ngelite nke metabolites iji mee ka excretion ahụ mee ka excretion. Enwere ike idozigharị sistemụ nrụọrụ nke imeju na ugt ma jiri ya mee ihe na-amụ anya nke ọgwụ ọgwụ na vitro.

Kpọtụrụ ugbu a Tinye na Cartzụ ahịa

Nkọwa nke ngwaahịa

Mkpado Ngwaahịa

Nke keibesti

Microsome - mkpụrụ - UGT Incubetions - 0.1m PBS (PH7.4)

Udi:
Na vitro Metabolism Kits
Ihe mba.:
0112b1.02
Ogo nkeji:
0.2ml * 50 nnwale
Anụ ahụ:
Umeji
Umu:
Enwe
Mmekọahụ:
Kenwaanyi
Ọnọdụ nchekwa na ụgbọ njem:
Chekwaa na - 70 Celsius C. Akọrọ akọrọ.
Dypedị Assay:
A na-akwụsi ike nke ọma
Sistemụ Ule:
Microdome
Akwukwo nyocha:
Na nyocha vitro nke nkwụsi ike metabolic

Nke gara aga: ISPASE SEDASE II Metabolic Kit, Beagle

Osote: IMPASASE IITILASIL KIT, enwe (Cynomolgus)

IMPASASE IITILASIL KIT, enwe (Cynomolgus)

Nkọwa mkpụmkpụ:

Nkọwa nke ngwaahịa

Mkpado Ngwaahịa

IMgbe onwe m, kpọnwụrụ akpọnwụ

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Iphase òké (iCrn / acd - 1) bile, agwakọta agwakọta

Iphase nkịta (Beagle), otu onyinye, nwanyị