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Iphase Phase II metabolicae stabilitas ornamentum, rat (SPRAGE - Dawley)

Short description:

Phase II metabolism, also known as the binding reaction, refers to the reaction in which phase I metabolites or prototype drugs combine with endogenous small molecules via phase II enzymes, leading to the reduction of toxicity, activity, or polarity of prodrugs. In phase II metabolismus, maxime commune reactionem est glucuronidation, in quo Uridine Diphosphate Glucuronic Acidum (Udpga) est tenetur in Microsomes per Catalyzation per Glucuronyl in microsomes. Et glucuronide formatae crescit aqua - solubility of metabolitarum ad augendae excretion. Et Phase II metabolicae ratio potest reparari ex iecoris microsomes et UGT et ad studium phase II metabolicae stabilitas medicamento candidati in vitro.

Product Detail

Product Tags

  • Product Discription

    Microsome - Substratum - Ugt Incubation System - 0.1M PBS (Ph7.4)

    • Genus:
      In vitro metabolism rhoncus
    • Item non.:
      0112D1.02
    • Unit Size:
      0.2ml * L test
    • TEXTUS:
      Iecur
    • Species:
      Rat
    • Sexus:
      Femina
    • Repono conditionibus et translationem:
      Store at - LXX ° C. Arida gelu tradidit.
    • Type Type:
      II Metabolicae stabilitate Ornamentum (Ugts)
    • Test ratio:
      Microsome
    • Scope of Application:
      In Vitro aestimationem de metabolicae stabilitatem

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