Ụlọ ADME Ngwa IPHASE II Metabolic Stability Kit, Rat(Sprague-Dawley)

IPHASE Phase II Metabolic Stability Kit,Rat(Sprague-Dawley)

Ngwa IPHASE II Metabolic Stability Kit, Rat(Sprague-Dawley)

Nkọwa dị mkpirikpi:

Metabolism nke Abụọ, nke a makwaara dị ka mmeghachi omume njikọ, na-ezo aka mmeghachi omume nke usoro nke metabolites ma ọ bụ prototype ọgwụ jikọtara ya na obere mkpụrụ ndụ endogenous site na enzymes nke II, na-eduga na mbelata nsị, ọrụ, ma ọ bụ polarity nke prodrugs. Na usoro nke II metabolism, mmeghachi omume na-emekarị bụ glucuronidation, n'oge nke uridine diphosphate glucuronic acid (UDPGA) na-ejikọta ya na prodrug site na catalyzation site na glucuronyl transferase na microsomes. Glucuronide emebere na-abawanye mmiri - solubility nke metabolites iji welie mkpochapụ ahụ. Enwere ike wughachi usoro metabolic nke abụọ site na njikọta nke microsomes imeju na UGT wee mụọ nkwụsi ike nke usoro II nke ndị na-achọ ọgwụ na vitro.

Kpọtụrụ ugbu a Tinye n'ụgbọ ịzụ ahịa

Nkọwa ngwaahịa

Mkpado ngwaahịa

Nkọwa ngwaahịa

Microsomes Substrate｜ UGT Incubation Sistemu｜ 0.1M PBS (pH7.4)

Otu:
In vitro metabolism ngwa ngwa
Ihe NO:
0112D1.02
Nha nkeji:
0.2ml*50 ule
Anụ ahụ:
Imeju
Ụdị:
Oke
Mmekọahụ:
Nwanyị
Ọnọdụ nchekwa na njem njem:
Na-echekwa na -70°C. Akpụrụ akpụ akpụ.
Ụdị nyocha:
Ngwa nke Metabolic Stability (UGTs) Nkeji II
Sistemụ ule:
Microsome
Oke ngwa:
Ntụle In vitro nke Metabolic Stability

Nke gara aga: Ngwa IPHASE II Ngwa nkwụsi ike Metabolic, Òké(ICR/CD-1)

Na-esote: Ngwa IPHASE II Metabolic Stability Kit, Rat(Sprague-Dawley)

Ngwa IPHASE II Metabolic Stability Kit, Rat(Sprague-Dawley)

Nkọwa dị mkpirikpi:

Nkọwa ngwaahịa

Mkpado ngwaahịa

IPHASE enwe(Cynomolgus) PBMC, oyi kpọnwụrụ

IPHASE Rat(Sprague-Dawley) Tissue Imeju,Nwanyị

IPHASE Minipig(Bama) Mpekere,Nwoke

Ihe ọṅụṅụ IPHASE Artificial Colon, Amonia

IPHASE òké NK Cells adịghị mma Isolation Kit