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C57BL/6, often referred to as "C57 black 6", "C57", or "black 6" (standard abbreviation B6), is a common inbred strain of laboratory mouse. It is widely used as a transgenic mouse in genetic testing to mimic human genetic defects.
Since the drug metabolizing enzyme activities gradually decrease with the prolongation of in vitro incubation time, traditional in vitro metabolism models have limitations such as short incubation tim
The in vivo alkaline comet assay has been increasingly used in the genotoxicity evaluation of compounds. ICH S2(R1) has included the liver comet assay as the 2nd in vivo test for tissues/endpoints; an
Revolutionary Therapeutics: Antibody-Oligonucleotide Conjugates (AOCs) – The Future of Precision Medicine
In the rapidly evolving world of biopharmaceuticals, Antibody-Oligonucleotide Conjugates
Recently, IPHASE, in conjunction with the Perelman School of Medicine at the University of Pennsylvania, co-authored an article in the journal Antibody Therapeutics (IF=4.56) titled "Development of a
Introduction to Rat Liver S9
Rat Liver S9 is a sub-cellular fraction obtained from liver tissue, particularly from rats, following a specific homogenization and centrifugation process. It contains a
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