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The in vivo alkaline comet assay has been increasingly used in the genotoxicity evaluation of compounds. ICH S2(R1) has included the liver comet assay as the 2nd in vivo test for tissues/endpoints; an
PDC in vitro ADME research model PDC takes into account the characteristics of both large and small molecules. Therefore, in vitro ADME research on it needs to take into account homing peptides, linke
The 63rd SOT ended perfectly, and the excitement of IPHASE-US never ends!
The 63rd Annual Meeting and Exposition of the American Society of Toxicology was successfully held from March 10-14, 2024, in
Introduction
T cells are an essential component of the immune system, playing a critical role in identifying and combating pathogens. The process of T cell activation is a complex, multi-step mechanis
Antibody-Drug Conjugate (ADC) is a relatively new type of biotechnology drug which couples small molecule therapeutic compounds to targeting antibodies/antibody fragment by linkers.
Introduction to Rat Liver S9
Rat Liver S9 is a sub-cellular fraction obtained from liver tissue, particularly from rats, following a specific homogenization and centrifugation process. It contains a
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