Tala Fou
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Mataupu Faavae o le PBMC Isolation Kit
O le tu'u'ese'eseina o le toto Mononuclear Cells (PBMC) ose auala taua i su'esu'ega fa'alesoifua maloloina ma fa'aoga falema'i. O nei sela e aofia ai lymphocytes (faataitaiga, sela T, sela B, sela NK) aFaitau atili -
IPHASE: Kometi su'esu'e pusa fa'afaigofieina in vitro genotoxicity su'esu'ega
O le in vivo alkaline comet assay ua faʻateleina le faʻaaogaina i le suʻesuʻeina o le genotoxicity o mea faʻapipiʻi. ICH S2(R1) ua aofia ai le liver comet assay o le 2nd in vivo test mo tissues/endpoints; aFaitau atili -
IPHASE Precision Microsomes Fa'asologa: Accelerators mo Su'esu'ega Fa'asaienisi
I le tulaga lautele o su'esu'ega fa'alesoifua maloloina ma vaila'au, ua fa'alauiloa e le IPHASE se fa'asologa o pusa biomicrosomes maualuga-fa'atinoga, e aofia ai pusa microsomes ate, pusa microsomes intestinal ma micros intestinal.Faitau atili -
Tala fou in vitro hepatocyte metabolism faʻataʻitaʻiga faʻafaigofieina lemu-metabolizing suʻesuʻega pharmacokinetic
Talu ai ona o le vailaʻau e faʻaaogaina le enzyme e faasolosolo malie ona faʻaitiitia i le faʻaumiumi o le incubation in vitro, o faʻataʻitaʻiga masani in vitro metabolism ei ai tapulaʻa e pei o le taimi faʻapuupuu puupuu.Faitau atili