Blog
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Solutions for in vitro mRNA drug metabolism studies
Introduction to mRNA drugs Messenger RNA (mRNA) is a sequence of nucleotides that encodes a protein, and in the cytoplasm is able to use organelles to express the encoded protein. mRNA drugs are chemiRead more -
Why are male Sprague Dawley rats used in research?
Introduction: Importance of Sprague Dawley Rats in Research Sprague Dawley rats have become an integral part of scientific research due to their unique characteristics and versatility in various expeRead more -
What is rat liver S9?
Introduction to Rat Liver S9 Rat Liver S9 is a sub-cellular fraction obtained from liver tissue, particularly from rats, following a specific homogenization and centrifugation process. It contains aRead more -
One-stop product solution for in vitro ADME research of peptide-drug conjugates
PDC in vitro ADME research model PDC takes into account the characteristics of both large and small molecules. Therefore, in vitro ADME research on it needs to take into account homing peptides, linkeRead more -
What do microsomes do in the liver?
Introduction to Liver Microsomes Microsomes are small vesicular fragments derived from the endoplasmic reticulum and are found within liver cells (hepatocytes). They play a crucial role in various bioRead more -
IPHASE: Principles of Frozen Section Kits
IPHASE, as a leader in biological reagents for in vitro research of innovative medicines, continues to introduce high-end research reagents in multiple fields and types based on years of research and development experience.Read more -
Good news: IPHASE joined hands with the University of Pennsylvania to develop new antibodies!
Recently, IPHASE, in conjunction with the Perelman School of Medicine at the University of Pennsylvania, co-authored an article in the journal Antibody Therapeutics (IF=4.56) titled "Development of aRead more -
Principle of PBMC Isolation Kit
The isolation of Peripheral Blood Mononuclear Cells (PBMC) is a crucial technique in biomedical research and clinical applications. These cells include lymphocytes (e.g., T cells, B cells, NK cells) aRead more -
IPHASE : Comet assay kits facilitate in vitro genotoxicity studies
The in vivo alkaline comet assay has been increasingly used in the genotoxicity evaluation of compounds. ICH S2(R1) has included the liver comet assay as the 2nd in vivo test for tissues/endpoints; anRead more -
IPHASE Precision Microsomes Series: Accelerators for Scientific Discovery
In the broad field of biomedical and drug discovery, IPHASE has launched a series of high-performance biomicrosomes kits, including liver microsomes kit, intestine microsomes kit and intestinal microsRead more -
Novel in vitro hepatocyte metabolism model facilitates slow-metabolizing pharmacokinetic studies
Since the drug metabolizing enzyme activities gradually decrease with the prolongation of in vitro incubation time, traditional in vitro metabolism models have limitations such as short incubation timRead more -
IPHASE successfully launched C57BL/6 Mouse Primary Hepatocyte
C57BL/6, often referred to as "C57 black 6", "C57", or "black 6" (standard abbreviation B6), is a common inbred strain of laboratory mouse. It is widely used as a transgenic mouse in genetic testing to mimic human genetic defects.Read more