Genotoxicity
Genotoxicity assays yog in-vitro thiab in-vivo tests siv los kuaj xyuas cov tshuaj uas ncaj qha lossis tsis ncaj qha cuam tshuam cov caj ces los ntawm cov txheej txheem sib txawv ntawm DNA kev puas tsuaj, uas tuaj yeem tshwm sim hauv cov noob hloov pauv thiab chromosomal aberrations. Cov kev puas tsuaj no yog cuab yeej cuab tam thiab pab txhawb rau ntau theem ntawm kev loj hlob ntawm malignant qog. Vim tias tsis muaj ib qho kev ntsuam xyuas tuaj yeem txheeb xyuas tag nrho cov ntsiab lus ntawm genotoxic, cov txheej txheem kev soj ntsuam yuav tsum siv kev sib xyaw ua ke ntawm cov kev sim sib txawv los ntsuas qhov muaj peev xwm genotoxic ntawm cov tshuaj ntsuam xyuas.
Leveraging ntau xyoo ntawm kev paub nyob rau hauv genotoxicity kev tshawb fawb project txoj kev loj hlob thiab nruam optimization, IPHASE tau tsim ntau yam in-vitro genotoxicity test kits: Ames, Mini-Ames. TK/HGPRT, Chromosomal Aberration, Micronucleus, Comet. Ntxiv mus, cov khoom tseem ceeb xws li Liver S9 Activation System, Giemsa staining reagents kuj muaj. Hauv cov ntsiab lus, cov khoom lag luam no tau tsim los txhawm rau txhim kho cov txheej txheem kev sim los ntawm kev tshem tawm cov txheej txheem kev npaj txaus ntshai thiab txhim kho kev kawm kev ntseeg tau zoo - tsim cov khoom tshwj xeeb kom kov yeej cov kev sib tw hauv kev sim hauv vitro genotoxicity.