Blank Biomatrix

Thaum lub sij hawm kev tshawb fawb bioanalytical, tshwj xeeb tshaj yog thaum huab hwm coj spectrometry - raws li txoj kev siv, matrix cuam tshuam yuav tsum tau soj ntsuam. Rau kev ntsuam xyuas cov nyhuv matrix, ADA cov kev tshawb fawb thiab cov kev tshawb fawb muaj feem xyuam, cov khoom siv roj ntsha dawb paug los ntawm tsawg kawg yog 6, 10 lossis 50 tus neeg pub dawb lossis cov khoom siv feem ntau yuav tsum tau ua.
IPHASE txhawb kev tshawb fawb tshuaj tshiab rau cov me me, peptides, tshuaj tiv thaiv kab mob thiab ADCs nrog cov tshuaj lom neeg muaj tseeb uas tau sau los ntawm kev sib xyaw - tus neeg pub dawb, sib xyaw ib leeg - kev sib deev, lossis ib leeg - poj niam txiv neej pub dawb. Peb kuj muab lwm cov matrices, dag matrices thiab simulated matrices rau cov kev tshawb fawb endogenous analyte, nrog rau cov matrices depleted ntawm cov khoom tshwj xeeb rau kev tshawb fawb endogenous.

TsiajHom

Cynomolgus liab, rhesus liab, marmoset, Beagle aub, SD nas, Wistar nas, Wistar Han nas, ICR/CD-1 nas, C57BL/6J nas, C57BL/6N nas, BALB/c nas, BALB/c liab qab nas, Nu/Nu liab qab nas, NSG nas, MID 1, SC - Transgenic nas, Hamster (Golden syrian), Guinea npua (Hartley), gerbil, paj rwb nas, Bama me me npua, Göttingen minipig, New Zealand luav, Feline, Bovine, yaj, ferret, thiab ntau dua

BioMatrix Pawg

1. 1. Native/Collected Matrices

Ntshav, ntshav, tag nrho cov ntshav, cerebrospinal kua, kua tsib, mis nyuj, dej aqueous, vitreous lom zem, tso zis, pais plab kua txiv, kua dej plab hnyuv, synovial kua, quav, synovium, adipose ntaub so ntswg, sciatic paj ntaub, cov nqaij mos, skeletal leeg nqaij, gastrocnemius cov ntaub so ntswg, lub raum cov ntaub so ntswg, cov ntaub so ntswg ntawm zes qe menyuam, pob txha pob txha, cov ntaub so ntswg vascular thiab cov ntaub so ntswg homogenize

• 2. IgG-kev ua kom muaj roj ntsha tsis zoo

IgG - depleted serum/plasma, IgM - depleted serum/plasma, IgA - depleted serum/plasma, IgE - depleted serum/plasma, IgD - depleted serum/plasma

1. B. Complement-ua kom ntshav qab zib

C1q - depleted serum, C2 - depleted serum, C3 - depleted serum, C4 - depleted serum, C5 - depleted serum, C6 - depleted serum, C7 - depleted serum, C8 - depleted serum, C9 - depleted serum, C3 / C4 - depleted serum, C3/ Complement factor D - depleted serum, Complement factor H - depleted serum, Complement factor I - depleted serum, Complement factor P - depleted serum, C1q + complement factor D - depleted serum, C3 + complement factor B - depleted serum, C4 + complement factor B - depleted serum, C5 + ntxiv serum B-

1. C. Lipoprotein- ntshav qabzib/plasma

Low-density lipoprotein (LDL) - depleted serum/plasma, Tsawg heev - ceev lipoprotein (VLDL) - depleted serum/plasma, Siab - ceev lipoprotein (HDL) - depleted serum/plasma, Oxidised lipoprotein - depleted serum/plasma, Acetylated lipoprotein - depleted serum/plasma

1. D. Vitamin-, hormone- thiab amino acid - depleted serum/plasma
   • Vitamin D - depleted serum/plasma, Vitamin A (retinol) - depleted serum/plasma, Vitamin K - depleted serum/plasma, Vitamin E - depleted serum/plasma, Vitamin B - depleted serum/plasma, Catecholamine - depleted serum/plasma, Steroid - depleted serum/plasma/, Neurotransmitter - depleted serum/plasma, Amino acid - depleted serum/plasma

1. E. Purified proteins

• Purified IgG, Purified IgM, Purified IgA, Purified IgE, Purified IgD, Purified albumin, Purified siab - ceev lipoprotein (HDL), Purified low - ceev lipoprotein (LDL), Purified tsawg heev - ceev lipoprotein (VLDL)

3. 3. Artificial / Simulated / Alternative Matrices

Artificial plasma, cov khoom siv dag zog, cov ntshav tsim tag nrho, cov khoom siv cerebrospinal fluid, cov zis tso zis, cov kua dej ua kom muaj zog, cov tshuaj lom neeg muaj zog, cov kua txiv hmab txiv ntoo thiab cov kua txiv hmab txiv ntoo.