Ib qho - Tsis txhob kua tshuaj rau hauv Vitro Admo cov kev tshawb fawb ntawm AOCS cov tshuaj

Tshuaj Ntsuam Xyuas: antibody - oligonucleotide conjugates (AOCs) - lub neej yav tom ntej ntawm cov tshuaj kho mob

Hauv kev hloov kho ceev nrawm nrawm ntawm biopharraceuticals,Tshuaj tiv thaiv kab mob oligonucleotide conjugates (AOCs)yog tawm los ua kev kawm cov tshuaj ntawm cov tshuaj, sib txuas ua ke ntawm cov tshuaj tiv thaiv zoo nrog cov gene - kev tswj hwm muaj peev xwm ntawm oligonucleides. Cov kev kho mob tshiab no tau tsim los ua kom xa cov kab mob oligonucleotides-luv ntawm DNA lossis RNA-ncaj qha rau cov hlwb tshwj xeeb lossis cov ntaub so ntswg, ua kom muaj qhov tsis muaj tseeb hauv kev kho mob. Qhov no ob qho kev ua no ua kom pom kev tshiab qhib cov kev nyuaj tshiab rau cov mob hnyav xws li mob qog nqaij hlav, thiab cov kab mob hnyav tiv thaiv kab mob.

Vim li cas AOCs yog cov pauv kev ua si

AoCs yog tsim ntawm peb qhov tseem ceeb tseem ceeb: ib qho tshuaj tiv thaiv kab mob, ib qho oligonucleotide, thiab ib qho txuas. Qhov no yuav tsum tau ua kev zoo siab rau kev saib xyuas thaum kev loj hlob, tshwj xeeb tshaj yog hauv kev tshawb fawb ntawm lub phatrackas. Tsis zoo li cov tshuaj ib txwm muaj yeeb tshuaj me Nyob rau hauv kev tsim kho tshuaj rau thaum ntxov, nws yog qhov tseem ceeb rau kev coj uaNtshav / Ntshav Saib Xyuas Kev Ua Vaj TseTxhawm rau kom ntseeg tau cov oligonucleotide tivthaiv tsis muaj zog, vim tias lawv muaj kev cuam tshuam rau kev cuam tshuam los ntawm nucleendes. Qhov kev ruaj ntseg thiab tso tawm ntawm Oligonucleotide hauv cov hlwb cov hlwb yog qhov tseem ceeb rau kev ua tiav ntawm AOCs.

Tsis tas li ntawd, cov qauv ntawm txuas ntawm oligonucleotide rau cov tshuaj tiv thaiv kev cuam tshuam ncaj qha rau cov tshuaj zoo li cas hauv lub cell, tshwj xeeb hauv cov lej lysosomes. Qhov tseem ceeb no txhais tau tias ocs yuav tsum tau tshwj xeeb bioanalytical cov hau kev rau cov kws tshawb fawb tshuaj papanokinetic, ua rau qhov kev ntsuas ntawm lawv cov qauv thiab kev tshuaj ntsuam xyuas tsis tau rau lawv txoj kev ua tau zoo.


Los ntawm Oleksandr Koniev - Tus kheej ua haujlwm, CC los ntawm - SA 4.0

Iphase: Koj tus khub hauv AOC innovation

Ntawm Iphase, peb tau txhawb nqa nthwv dej ntawm AOC cov tshuaj tsim kho kev sib cav nrog txiav - NtugNyob rau hauv vitro Bio - ReagentsCov. Nrog cov ntau ntawm bio - reagents, peb pab cov kws tshawb fawb tshuaj tau ua tiav cov tshuaj ntsuam kev tawg ua kom muaj kev siv tshuaj yeeb thiab kev loj hlob. Peb cov ntaub ntawv tshawb fawb dav dav ntawm cov kev tshawb fawb uas nyob rau hauv kev tshawb fawb, macromolecules, muab cov cuab yeej tseem ceeb uas yuav tsum tau ua kom ntseeg tau tias ua tiav thaum ntxov kev txhim kho kev siv tshuaj.

Nrog xyoo kev txawj ntse thiab kev tsim kho tshiab, Iphase muaj aUa kom tiav suite ntawm hauv cov kev tshawb fawb vitro reagentsrau cov tshuaj AOC thiab dhau mus. Txawm hais tias koj tab tom tsim cov oocules, lossis lwm chav kawm tshuaj, Iphas tau cog lus los muab cov kev daws teeb meem koj xav tautsav koj txoj kev tshawb nrhiav tom ntejThiab nqa cov tiam lwm zaus ntawm kev kho mob rau lub neej.

Tshawb nrhiav lub neej yav tom ntej kev txhim kho yeeb tshuaj nrog Mhashase-Txoj kev siv tshuaj kho mob tsim nyog cov cuab yeej precision.