Cum continua progressionem de biotechnology, in progressionem targeted antuscumor medicinae ut parva molecule componit, oligonucleotides et biologica fecit celeri progressus, inter quae Sirna et Maluit electiones ad progressionem sunt maxime popularibus et malle et ad Development est maxime popularibus et ad medicamentis et malle a pluribus medicamentis et pharmaceutical societates. Vitro probat necessaria explorare stabilitatem salutem medicinae etlysosomesSunt necessaria in vitro metabolism investigationis products in progressionem Sirna / Rnai et Adc medicinae.
Iphase Products
|
Item No. |
Product Name |
Specificatio |
|
CCL μl, II mg / ml |
||
|
CCL μl, II mg / ml |
||
|
CCL μl, II mg / ml |
||
|
CCL μl, II mg / ml |
||
|
CCL μl, II mg / ml |
||
|
A - I ml, b - μl |
Introductio ad Lysosomes
Lysosomessunt una - membrana organelles in Eukaryotic cellulis qui conteram et biomolucules ut proteins, nucleic acida et polysaccharides, et primum inventa in rat Hepatocytes in MCMLV per Belgian Scholar Cristina de Duve (MCMXVII - MMXIII) et aliis. Lysosomes have various shapes, usually vesicular structures of 0.025-0.8 μm, and contain more than 60 hydrolytic enzymes such as acid phosphatase, ribonuclease, deoxyribonuclease, histone protease, and acetyltransferase, which are a group of hydrolytic enzymes with an optimal pH in the acidic region, and the optimal pH of the Hydrolytic enzymes est 3.5 - 5.5.In visum de structuris specifica de lysosomes et acidic operantes amet, substantiae quae positivum acidum phosphatase operatio sunt plerumque identified quod Lysosomes.
Diagram lysosomes. Imago creata a FigDraw.
Characteres Lysosomes
Sicut lysosomes quod opus in acidic regionum, eorum enzymes continere tres characteres:
I) et lysosomal superficiem est altus glycosylated, quod adjuvat protegat se ab enzymatic hydrolysis. Membrana proteins plerumque glycoproteins, et in interiore superficies lysosomal membrana est negative præcepit, quod adjuvat enzymes in lysosomes manere liberum. Hoc est momenti ad exercens normalis munus et prohibere cellulam se ab digesta;
II) Omnes hydrolytic enzymes sunt optimally activae ad de PH = V, sed in circuitu cytoplasm habet PH = 7.2. Lysosomal membrana habet specialem transporter dapibus quod potest utor industria of ATP hydrolysis ad sentinam H + (hydrogenii ions) a cytoplasm in lysosomes ut ponere eius PH = V;
III) in enzymes in lysosomes exercere eorum catabolic partes tantum cum hydrolyzed substantia intrat Lysosomes. Semel in lysosomal membrana est ruptured et hydrolyzing enzymes evadere, cellular autolysis et consequuntur.
Munus et genuslysosomes
Pelagus partes lysosomes est concoctionem, an intracellular digestive organum, et cellular autolysis, defensionem, et utendo quaedam substantiae sunt omnia ad lysosomal digestionem. Effectus munus est duplex, nimirum, fusionem cum cibum vesiculae ad concoquere cibum in biomolucules et digestio senescent organelles et biomolucules formatae in processus of se - renovatio organismi.
Lysosomes dividitur in primaria lysosomes secunda lysosomes et RELICTUM corpus secundum diversas gradus perficiendi physiologica munera.
Post tempus: MMXIV - XI - V 14:19:09