Lysisomes (Tritosomes): Onye na-ebu amụma na usoro nnwale vitro maka Catabolism ma ọ bụ ụlọ ọrụ lysisoMal

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Okwu Mmalite nkeLysisomes
Onye Kraịst derọsoo na 1950 ma guzobere dị ka etiti mbibi nke mmebi na metabolism na sel. Lysisomes bụ otu akpụkpọ ahụ, akpụkpọ ahụ ike, heanogeneus dị iche na ọnọdụ, morphology, nha, na mkpụrụ. Akpụkpọ anụ lysisomal nwere ọtụtụ narị protein proteins, gụnyere ọtụtụndị na-ebugharịna oon ọwa. Lysisomal ọtụtụ ndị ahịa VYSUNIT V - Atpase na-enwe na-eme ka acidic lysisomal lumen. Nke a dị ala (4.5 - 5.5) na-arụ ọrụ> 50 lrosomal na-agbadata macromolecules gụnyere protein, nucleic acid, na carbohydrates. Lysisomes na-anata ma na-agbadata ihe ndị na-agbago ma na-agbari egwu, na-eme ihe dị ka callototic call, gụnyere Mitochondria, na Lọnomomes. Ya mere, a na-ewere Lọnosomes ogologo oge ka "binycling bin" nke sel.

Tritosome

Tritesomes bụ usoro dị iche iche nke metụtara usoro cellular dị iche iche, ọkachasị na usoro nke usoro metabolicy na mmezi nke cellulasis. A na-amụkarị tritor na ọrụ ha n'ime ụdị organism. Akụkụ nkọwapụta nke ụlọ ndị a bụ ihe mejupụtara ha pụrụ iche, nke na-enye ha ohere ịme ọrụ ndị na-atọ ụtọ maka nlanarị na sel. Rulimer na-eme obodo wyposomes Nke ahụ ejiriwo Tylocapol dị (triton WR 1339), na-abụghị nke ionic froctant. Lysisomes nwere ihe ngosi Tylosapol belatara njupụta, enwere ike ịrụ ọrụ nke ọma site na mitochondria, na-emebi ihe ndị nwere oke egbu egbu.

Ngwa nke Lyssomes
Ọgwụ acid na lySosomes
Ọgwụ acid nucleic acid na-ezo aka na iberibe nke nucleotides na usoro ụfọdụ nwere ike ijikọ akụkụ ụfọdụ nke Mrnas iji mezuo nsonaazụ ọgwụgwọ. Ọgwụ na-acha acid nucleic gụnyere mgbochi oligonucleotide (ASOS), obere amnamers RNA, asna), ASNA na SERNA bụ nke kachasị ugbu a nke obere nyocha acids.

Mgbe nchịkwa acid acid na-eme ka ọ bụrụ na ọgwụ Nucleic nke mbụ iji zere ngọngọ na plasma na anụ ahụ, na-ejikọta contomas, na-ejikọ ya na ihe mgbaru ọsọ Mee iji mezuo usoro ịba ọcha. Enwere ike iji Lysisomes dị ka usoro nnwale nke dị iche iche iji nyochaa mgbanwe ndị acidification ọgwụ na-agbanwe agbanwe mgbe ihe nke Lọlị, inye nkwado data maka nyocha nke obere nucleic acid.

Antunod - ogwu conjugate (adc) na Lọdisomes
Antod - ogwu) bụ ụdị ọgwụ ọhụụ nke ihe ọmụmụ na ndị di na nwunye na-ejikọkarị ọgwụ mgbochi ma ọ bụ ndị uwe ojii. Ọ nwere ike ịkwalite ọgwụ na nkwụsi ike, belata nsi na-egbu egbu na nsonaazụ ya, ma melite ndeksi ọgwụgwọ. O nwere ma ihe na-egbu egbu nke obere molecule ọdịnala na ebumnuche ọgwụ ọgwụ mgbochi. A na-ejikarị ya na usoro ọgwụgwọ nke mgbochi - Elu ma ọ bụ ọrịa ndị ọzọ.

Mgbe ịbanyechara ahụ, The Adc Molecules nwere ike igbochi ihe mgbochi ahụ n'elu sel ahụ site na nduzi nke antibodies monoclodies, nafee n'ihu na mkpụrụ ndụ zube. The Adc Molecules na-abanye sel (tumadi na lysinomes) nwere ike ịhapụ obere moxins (i.e. ADC na-achọ egbe na-arụ ọrụ na-arụ ọrụ ma hapụ obere ụmụ agbọghọ na-arụ ọrụ na-arụ ọrụ na-arụ ọrụ, na-ebugharị na-aga na-aga igwe na-efe efe ma ọ bụ nucelus. Na nnwale vitro nke adc na Lyssomomes nwere ike ịnwale ma enwere ike ịkpụ ndị ọrụ ahụ nke ọma site na igwe ndị na-ahụ maka ọgwụ ọjọọ ọ na-ebu, na-enye ya na Ngwá Ọrụ Nchọpụta Virro.

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Arụrụ ọrụ Enpyme: Achọlitela ihe na-emeju anya na katipsin b na acid phosphatase, na Enzyme ọrụ yiri nke ngwaahịa ndị a ebubata.
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