Lysosomes, gabobin kan salon - narkewa

Tare da ci gaba da ci gaba na ilimin halittu, ci gaban maganganun maganganu da aka yi niyya kwayoyin cuta kamar yadda magunguna masu yawa na masana'antu suka fi so. A cikin gwaje-gwajen Vitro suna da mahimmanci don bincika kwanciyar hankali da amincin magunguna, daLysosomesShin ba makawa a cikin samfuran bincike na Vitro na Vitro na Vitro A cikin ci gaban Sirna / Rnaai da adc.

Kayayyakin iphayan

Gabatarwa zuwa Lysosomes

Lysosomesba su da aure - membrane norganelles a cikin sel Eukaryotic sel waɗanda ke karya biomoccytes sun sunadarai a 1955 daga Semon Makarantar Crisacytes a 1955 ta hanyar malamin Bature Crisacytes a 1955 ta hanyar malamin Batiriya Crisacytes a 1955 ta hanyar malamin Batir - Lysosomes suna da siffofi iri daban-daban, yawanci a cikin tsarin veesicular na 0.025 - 0.8 emphytic enzymes tare da enzylantic enzymes tare da ingantaccen ph a yankin acidic, da kuma mafi kyau duka ph na Hydrolytic Enyzymes shine 3.5.5 Duba game da tsarin tsarin lysosomes da kuma acidic aiki da ake gano ayyukan acidphatase yawanci ana gano su a matsayin Lysosomes.

Zane na lysosomes. Hoton da aka kirkira ta Figdraw.

Halaye na lysosomes

Kamar yadda Lysosomes da ke aiki a cikin yankuna na acidic, enzymes su kunshe da halaye uku:

1) Fuskar lysosomal tana da glycosylated, wanda ke taimakawa kare kanta daga enzymatic hydrolysis. Sunadar membrane sune glycoproteins mafi yawa glycopeins, da kuma a ciki na ciki na membrane da aka zalunta, wanda ke taimaka wa enzymes a cikin lysosomes su kasance kyauta. Wannan yana da mahimmanci don motsa jiki na al'ada da kuma hana tantanin da kanta daga narkewa;

2) Duk enzymel na hydrolytic enzymes suna aiki sosai a game da PH = 5, amma kewayensu yana da pH = 7.2. Membrane membrane ta ƙunshi furotin mai wucewa na musamman wanda zai iya amfani da ƙarfin ATP Hydrolysis zuwa famfo H + (hydrogen ions a cikin lysosomes domin kula da PH = 5;

3) enzymes a cikin lysosomes suna motsa jiki aikinsu ne kawai lokacin da kayan hydryzed ya shiga lysosomes. Da zarar membrane membrane ke ruptraned da enzymes na hydrolyzing tserewa, salon ruhi zai haifar.

Aiki da rarrabuwaLysosomes

Babban aikin lysosomes yana narkewa, ƙwayar ƙwayar cuta, da kuma amfani da kayan sel, kariya, da kuma amfani da wasu abubuwa dukansu suna da alaƙa da narkewa mai narkewa. Ayyukan zartarwa ne ninki biyu, wato, fada tare da vession abinci don narke abinci cikin biommeles da narkewar kwayar halitta - Sabunta kwayar halitta.

Lysosomes za a iya rarraba zuwa farkon Lysosomes na farko, Lysosomes sakandare da jikin saura gwargwadon matakai daban-daban na cim ma ayyukansu na zahiri.