Ntxias
Thaum ua tau kev soj ntsuam ntawm cov tshuaj, qhov tseem ceeb ntawm kev ntsuam xyuas kws tshuaj ntsuam kws tshuaj xyuas, kev xa tawm, cov metabolism, thiab excepeties yuav tsum tau elucidated thaum lub sij hawm kev tsim tshuaj. Cov metabolism, lossis cov xyoob ntoo ua haujlwm, yog hais txog cov txheej txheem uas unigoes tshuaj hloov kho rau kev nqus thiab tshem tawm hauv lub cev. Muab faib ua theem i & II metabolism, biotransformize mas feem ntau tshwm sim hauv kev mob siab, thiab tseem nyob hauv lwm lub plab zom mov, raum, mob ntsws, ntshav, thiab tawv nqaij.
Qhov teeb meem tseem ceeb, cov teeb meem tseem ceeb ntawm kev tshawb pom cov tshuaj tiv thaiv kev sib txheeb kom haum rau tib neeg cov tshuaj, tshuaj muaj txiaj ntsig thiab kev nyab xeeb. Ob peb xyoos dhau los, lub cuab tam tau tsim muaj ntau cov khoom lag luam xws li kev siv tshuaj metabolism suav nrog kev ruaj khov ruaj khov, kev sib luag metabolic, enzyme inhibition (IC50). Tsis tas li ntawd, cov nyiaj nruab nrab thiab cov qauv tseem muaj txiaj ntsig zoo li cov hepatocytes, s9 feem thiab plab hnyuv roj hmab, cyy recombinases sau los ntawm cov tsiaj tshwj xeeb ntawm ntau lub xeev.